catalog number :
MBS126277
products full name :
KRT23 Polyclonal Antibody
products short name :
[KRT23]
products name syn :
[K23; CK23; HAIK1]
other names :
[Keratin, type I cytoskeletal 23; Keratin, type I cytoskeletal 23; keratin, type I cytoskeletal 23; CK-23; keratin-23; cytokeratin 23; cytokeratin-23; histone deacetylase inducible keratin 23; type I intermediate filament cytokeratin; hyperacetylation-inducible type I keratin; keratin 23 (histone deacetylase inducible); Cytokeratin-23; CK-23; Keratin-23; K23]
products gene name :
[KRT23]
other gene names :
[KRT23; KRT23; K23; CK23; HAIK1; CK-23; K23]
uniprot entry name :
K1C23_HUMAN
reactivity :
Human, Mouse
purity :
Affinity Purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
storage stability :
Store at -20°C. Avoid freeze / thaw cycles.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:100
image1 heading :
Western Blot (WB)
other info1 :
Calculated MW: 33kDa/48kDa. Observed MW: 48 kDa
other info2 :
Immunogen: Recombinant protein of human KRT23. Calculated Molecular Weight: 48kDa
products categories :
Polyclonal
products description :
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants.
ncbi summary :
The protein encoded by this gene is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
uniprot summary :
K23: a type I cytoskeletal keratin. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. There are two types of cytoskeletal and microfibrillar keratin: type I (acidic; 40-55 kDa) [K9 to K20] and type II (neutral to basic; 56-70 kDa) [K1 to K8]. Both a basic and an acidic keratin are required for filament assembly. Protein type: Cytoskeletal. Chromosomal Location of Human Ortholog: 17q21.2. Cellular Component: intermediate filament. Molecular Function: structural molecule activity