product summary
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company name :
MyBioSource
product type :
antibody
product name :
VDAC1 Polyclonal Antibody
catalog :
MBS126096
quantity :
0.05 mg
price :
230 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot, immunohistochemistry
more info or order :
product information
catalog number :
MBS126096
products type :
Antibody
products full name :
VDAC1 Polyclonal Antibody
products short name :
VDAC1
products name syn :
VDAC1; MGC111064; PORIN; PORIN-31-HL
other names :
Voltage-dependent anion-selective channel protein 1; Voltage-dependent anion-selective channel protein 1; voltage-dependent anion-selective channel protein 1; porin 31HL; porin 31HM; plasmalemmal porin; outer mitochondrial membrane protein porin 1; voltage-dependent anion channel 1; Outer mitochondrial membrane protein porin 1; Plasmalemmal porin; Porin 31HL; Porin 31HM
products gene name :
VDAC1
other gene names :
VDAC1; VDAC1; PORIN; VDAC-1; VDAC; VDAC-1; hVDAC1
uniprot entry name :
VDAC1_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
283
purity :
Affinity Purification
concentration :
1mg/ml
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB), Immunohistochemistry (IHC)
app notes :
WB: 1:500 - 1:2000. IHC: 1:50 - 1:200. IF: 1:50 - 1:200
other info1 :
Species: Human. Route: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human VDAC1. Calculated Molecular Weight: 31kDa
products categories :
Polyclonal
products description :
Voltage-dependent anion channel (VDAC), ubiquitously expressed and located in the outer mitochondrial membrane, is generally thought to be the primary means by which metabolites diffuse in and out of the mitochondria (1). In addition, this channel plays a role in apoptotic signaling. The change in mitochondrial permeability characteristic of apoptosis is mediated by Bcl-2 family proteins, which bind to VDAC, altering the channel kinetics (2). Homodimerization of VDAC may be a mechanism for changing mitochondrial permeability and supporting release of cytochrome c (3). In mammalian cells, there are three VDAC isoforms, VDAC1, which is the most widely expressed isoform, as well as VDAC2 and VDAC3 (4,5).
ncbi gi num :
130683
ncbi acc num :
P21796.2
uniprot acc num :
P21796
ncbi mol weight :
283
ncbi pathways :
Calcium Signaling Pathway 83050!!Calcium Signaling Pathway 459!!HTLV-I Infection Pathway 373901!!HTLV-I Infection Pathway 373889!!Huntington's Disease Pathway 83100!!Huntington's Disease Pathway 512!!Influenza A Pathway 217173!!Influenza A Pathway 217150!!Metabolism Of Proteins Pathway 106230!!Mitochondrial Protein Import Pathway 576261
ncbi summary :
This gene encodes a voltage-dependent anion channel protein that is a major component of the outer mitochondrial membrane. The encoded protein facilitates the exchange of metabolites and ions across the outer mitochondrial membrane and may regulate mitochondrial functions. This protein also forms channels in the plasma membrane and may be involved in transmembrane electron transport. Alternate splicing results in multiple transcript variants. Multiple pseudogenes of this gene are found on chromosomes 1, 2 3, 6, 9, 12, X and Y.[provided by RefSeq, Sep 2010]
size :
0.05 mg
price :
230 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
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