catalog number :
MBS125960
products full name :
TJP2 Polyclonal Antibody
products short name :
TJP2
products name syn :
ZO-2: MGC26306; X104; ZO-2; ZO2
other names :
Tight junction protein ZO-2; Tight junction protein ZO-2; tight junction protein ZO-2; zona occludens 2; zonula occludens protein 2; Friedreich ataxia region gene X104 (tight junction protein ZO-2); tight junction protein 2; Tight junction protein 2; Zona occludens protein 2; Zonula occludens protein 2
products gene name :
TJP2
other gene names :
TJP2; TJP2; ZO2; X104; PFIC4; DFNA51; DUP9q21.11; C9DUPq21.11; X104; ZO2
uniprot entry name :
ZO2_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity Purification
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB), Immunofluorescence (IF)
app notes :
WB: 1:500 - 1:2000. IF: 1:50 - 1:100
other info1 :
Species: Human. Route: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human TJP2. Calculated Molecular Weight: 134kDa
products categories :
Polyclonal
products description :
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]
ncbi pathways :
Apoptosis Pathway 105648!!Apoptotic Cleavage Of Cell Adhesion Proteins Pathway 105680!!Apoptotic Cleavage Of Cellular Proteins Pathway 105678!!Apoptotic Execution Phase Pathway 105677!!Programmed Cell Death Pathway 1127510!!Signal Transduction Pathway 477114!!Signaling By Hippo Pathway 576275!!Tight Junction Pathway 83071!!Tight Junction Pathway 482!!Validated Targets Of C-MYC Transcriptional Repression Pathway 169353
ncbi summary :
This gene encodes a zonula occluden that is a member of the membrane-associated guanylate kinase homolog family. The encoded protein functions as a component of the tight junction barrier in epithelial and endothelial cells and is necessary for proper assembly of tight junctions. Mutations in this gene have been identified in patients with hypercholanemia, and genomic duplication of a 270 kb region including this gene causes autosomal dominant deafness-51. Alternatively spliced transcripts encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]