product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Paralemmin-1 (PALM)
catalog :
MBS1259184
quantity :
0.05 mg (E-Coli)
price :
190 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1259184
products type :
Recombinant Protein
products full name :
Recombinant Human Paralemmin-1 (PALM)
products short name :
Paralemmin-1 (PALM)
products name syn :
Paralemmin-1; Paralemmin
other names :
paralemmin-1 isoform 2; Paralemmin-1; paralemmin-1; paralemmin; Paralemmin
products gene name :
PALM
products gene name syn :
PALM; KIAA0270
other gene names :
PALM; PALM; KIAA0270
uniprot entry name :
PALM_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-384, Mature full length protein
sequence length :
384
sequence :
MEVLAAETTSQQERLQAIAEKRKRQAEIENKRRQLEDER
RQLQHLKSKALRERWLLEGTPSSASEGDEDLRRQMQDDE
QKTRLLEDSVSRLEKEIEVLERGDSAPATAKENAAAPSP
VRAPAPSPAKEERKTEVVMNSQQTPVGTPKDKRVSNTPL
RTVDGSPMMKAAMYSVEITVEKDKVTGETRVLSSTTLLP
RQPLPLGIKVYEDETKVVHAVDGTAENGIHPLSSSEVDE
LIHKADEVTLSEAGSTAGAAETRGAVEGAARTTPSRREI
TGVQAQPGEATSGPPGIQPGQEPPVTMIFMGYQNVEDEA
ETKKVLGLQDTITAELVVIEDAAEPKEPAPPNGSAAEPP
TEAASREENQAGPEATTSDPQDLDMKKHRCKCC
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi gi num :
93141029
ncbi acc num :
NP_001035224.1
ncbi gb acc num :
NM_001040134.1
uniprot acc num :
O75781
ncbi mol weight :
37,157 Da
ncbi summary :
This gene encodes a member of the paralemmin protein family. The product of this gene is a prenylated and palmitoylated phosphoprotein that associates with the cytoplasmic face of plasma membranes and is implicated in plasma membrane dynamics in neurons and other cell types. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
paralemmin: Involved in plasma membrane dynamics and cell process formation. Isoform 1 and isoform 2 are necessary for axonal and dendritic filopodia induction, for dendritic spine maturation and synapse formation in a palmitoylation-dependent manner. Belongs to the paralemmin family. 2 isoforms of the human protein are produced by alternative splicing. Chromosomal Location of Human Ortholog: 19p13.3. Cellular Component: nucleoplasm; filopodium membrane; intracellular membrane-bound organelle; axon; integral to plasma membrane; apicolateral plasma membrane; basolateral plasma membrane; cytoplasmic membrane-bound vesicle; plasma membrane; nucleus. Molecular Function: protein binding; D3 dopamine receptor binding. Biological Process: positive regulation of filopodium formation; regulation of cell shape; synapse maturation; negative regulation of dopamine receptor signaling pathway; negative regulation of adenylate cyclase activity; cytoskeleton organization and biogenesis; cell motility
size1 :
0.05 mg (E-Coli)
price1 :
190 USD
size2 :
0.05 mg (Yeast)
price2 :
260
size3 :
0.2 mg (E-Coli)
price3 :
460
size4 :
0.2 mg (Yeast)
price4 :
600
size5 :
0.5 mg (E-Coli)
price5 :
750
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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