product summary
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company name :
MyBioSource
product type :
antibody
product name :
MYCN Polyclonal Antibody
catalog :
MBS125752
quantity :
0.05 mg
price :
285 USD
clonality :
polyclonal
host :
rabbit
conjugate :
nonconjugated
reactivity :
human, mouse, rat
application :
western blot
more info or order :
product information
catalog number :
MBS125752
products type :
Antibody
products full name :
MYCN Polyclonal Antibody
products short name :
MYCN
products name syn :
N-Myc: NMYC; ODED; MODED; N-myc; MYCNOT; bHLHe37
other names :
N-myc proto-oncogene protein; N-myc proto-oncogene protein; N-myc proto-oncogene protein; pp65/67; oncogene NMYC; neuroblastoma MYC oncogene; class E basic helix-loop-helix protein 37; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; Class E basic helix-loop-helix protein 37; bHLHe37
products gene name :
MYCN
other gene names :
MYCN; MYCN; NMYC; ODED; MODED; N-myc; bHLHe37; BHLHE37; NMYC; bHLHe37
uniprot entry name :
MYCN_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Mouse, Rat
sequence length :
464
purity :
Affinity Purification
concentration :
1mg/ml
storage stability :
Store at -20 degree C (regular) or -80 degree C (long term). Avoid freeze / thaw cycles. Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
tested application :
Western Blot (WB)
app notes :
WB: 1:500 - 1:2000
other info1 :
Species: Human. Route: Recombinant Protein
other info2 :
Immunogen: Recombinant protein of human MYCN. Calculated Molecular Weight: 65kDa
products categories :
Polyclonal
products description :
MYCN, also named as BHLHE37 and NMYC, is a transcription factor. It is primarily expressed in normal developing embryos and is thought to be critical in brain and other neural development. It is often amplified in human neuroblastomas. IR34A can suppress MYCN expression, it suggest MYCN has a role in cell growth. The expression of the MCYN is upregulated in a variety of human tumors, most requently neuroblastoma, where the level of expression appearts to increase as teh tumor progress.
ncbi gi num :
127604
ncbi acc num :
P04198.2
uniprot acc num :
P04198
ncbi mol weight :
464
ncbi pathways :
Transcriptional Misregulation In Cancer Pathway 523016!!Transcriptional Misregulation In Cancer Pathway 522987
ncbi summary :
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
size :
0.05 mg
price :
285 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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