protein

Recombinant Influenza A virus Matrix protein 1 (M)

MBS1256969

0.01 mg (E-Coli)

235 USD

Recombinant Protein

Recombinant Influenza A virus Matrix protein 1 (M)

[Matrix protein 1 (M)]

[Matrix protein 1; M1]

[Matrix protein 1; Matrix protein 1]

[M; M1]

M1_I43A0

E Coli or Yeast or Baculovirus or Mammalian Cell

[1-252. Full Length]

MSLLTEVETYVLSIVPSGPLKAEIAQRLEDVFAGKNTDL
EALMEWLKTRPILSPLTKGILGFVFTLTVPSERGLQRRR
FVQNALNGNGDPNNMDRAVKLYRKLKREITFHGAKEIAL
SYSAGALASCMGLIYNRMGAVTTEVAFGLVCATCEQIAD
SQHRSHRQMVTTTNPLIRHENRMVLASTTAKAMEQMAGS
SEQAAEAMEVASQARQMVQAMRAIGTHPSSSAGLKNDLL
ENLQAYQKRMGVQMQRFK

>=90%

Liquid containing glycerol

Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

SDS-PAGE

Species: Influenza A virus (strain A/USA:Iowa/1943 H1N1)

Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place. Determines the virion's shape: spherical or filamentous. Clinical isolates of influenza are characterized by the presence of significant proportion of filamentous virions, whereas after multiple passage on eggs or cell culture, virions have only spherical morphology. Filamentous virions are thought to be important to infect neighboring cells, and spherical virions more suited to spread through aerosol between hosts organisms

229890350

A4GCL0.1

A4GCL0

11,178 Da

Plays critical roles in virus replication, from virus entry and uncoating to assembly and budding of the virus particle. M1 binding to ribonucleocapsids (RNPs) in nucleus seems to inhibit viral transcription. Interaction of viral NEP with M1-RNP is thought to promote nuclear export of the complex, which is targeted to the virion assembly site at the apical plasma membrane in polarized epithelial cells. Interactions with NA and HA may bring M1, a non-raft-associated protein, into lipid rafts. Forms a continuous shell on the inner side of the lipid bilayer in virion, where it binds the RNP. During virus entry into cell, the M2 ion channel acidifies the internal virion core, inducing M1 dissociation from the RNP. M1-free RNPs are transported to the nucleus, where viral transcription and replication can take place ().

0.01 mg (E-Coli)

235 USD

0.05 mg (E-Coli)

320

0.1 mg (E-Coli)

535

0.05 mg (Yeast)

795

0.2 mg (E-Coli)

855

0.05 mg (Baculovirus)

1005

0.2 mg (Yeast)

1065

0.5 mg (E-Coli)

1125

0.5 mg (Yeast)

1205

0.05 mg (Mammalian-Cell)

1245

0.1 mg (Baculovirus)

1450

1 mg (E-Coli)

1725

0.5 mg (Baculovirus)

1895

1 mg (Yeast)

1900

0.1 mg (Mammalian-Cell)

2030

1 mg (Baculovirus)

2940