catalog number :
MBS125479
products full name :
IRF-3 Polyclonal Antibody
products short name :
IRF-3
other names :
Interferon regulatory factor 3; Interferon regulatory factor 3; interferon regulatory factor 3; interferon regulatory factor 3
products gene name :
IRF3
other gene names :
IRF3; IRF3; IRF-3
uniprot entry name :
IRF3_HUMAN
reactivity :
Human, Mouse, Rat
purity :
Affinity Purification
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunoprecipitation (IP)
other info1 :
Species: Human. Route: Recombinant Protein
products categories :
Polyclonal
ncbi pathways :
Activated TLR4 Signalling Pathway 106400!!Activation Of IRF3/IRF7 Mediated By TBK1/IKK Epsilon Pathway 187088!!Antiviral Mechanism By IFN-stimulated Genes Pathway 530760!!Apoptosis Pathway 198797!!Cytokine Signaling In Immune System Pathway 366171!!Cytosolic DNA-sensing Pathway 125137!!Cytosolic DNA-sensing Pathway 124833!!Cytosolic Sensors Of Pathogen-associated DNA Pathway 576255!!Epstein-Barr Virus Infection Pathway 585562!!Epstein-Barr Virus Infection Pathway 587115
ncbi summary :
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Nov 2011]