product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human respiratory syncytial virus B Fusion glycoprotein F0
catalog :
MBS1253087
quantity :
0.05 mg (E-Coli)
price :
180 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1253087
products type :
Recombinant Protein
products full name :
Recombinant Human respiratory syncytial virus B Fusion glycoprotein F0
products short name :
Fusion glycoprotein F0
other names :
fusion protein; Fusion glycoprotein F0; F
products gene name :
F
other gene names :
F; F; Protein F
uniprot entry name :
FUS_HRSVB
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
137-574 ;partial; Fusion glycoprotein F1 chain
sequence length :
574
sequence :
FLGFLLGVGSAIASGIAVSKVLHLEGEVNKIKNALLSTN
KAVVSLSNGVSVLTSKVLDLKNYINNQLLPIVNQQSCRI
SNIETVIEFQQKNSRLLEINREFSVNAGVTTPLSTYMLT
NSELLSLINDMPITNDQKKLMSSNVQIVRQQSYSIMSII
KEEVLAYVVQLPIYGVIDTPCWKLHTSPLCTTNIKEGSN
ICLTRTDRGWYCDNAGSVSFFPQADTCKVQSNRVFCDTM
NSLTLPSEVSLCNTDIFNSKYDCKIMTSKTDISSSVITS
LGAIVSCYGKTKCTASNKNRGIIKTFSNGCDYVSNKGVD
TVSVGNTLYYVNKLEGKNLYVKGEPIINYYDPLVFPSDE
FDASISQVNEKINQSLAFIRRSDELLHNVNTGKSTTNIM
ITTIIIVIIVVLLSLIAIGLLLYCKAKNTPVTLSKDQLS
GINNIAFSK
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products description :
During virus entry, induces fusion of viral and cellular membranes leading to delivery of the nucleocapsid into the cytoplasm. The fusogenic activity is inactive untill entry into host cell endosome, where a furin-like protease cleaves off a small peptide between F1 and F2. Interacts directly with heparan sulfate and may participates in virus attachment. Furthermore, the F2 subunit was identifed as the major determinant of RSV host cell specificity. Later in infection, proteins F expressed at the plasma membrane of infected cells can mediate fusion with adjacent cells to form syncytia, a cytopathic effect that could lead to tissue necrosis. The fusion protein is also able to trigger p53-dependent apoptosis.
products references :
Respiratory syncytial virus (RSV)SH and G proteins are not essential for viral replication in vitro clinical evaluation and molecular characterization of a cold-passaged, attenuated RSV subgroup B mutant.Karron R.A., Buonagurio D.A., Georgiu A.F., Whitehead S.S., Adamus J.E., Clements-Mann M.L., Harris D.O., Randolph V.B., Udem S.A., Murphy B.R., Sidhu M.S.Proc. Natl. Acad. Sci. U.S.A. 94:13961-13966(1997) Fatty acid acylation of the fusion glycoprotein of human respiratory syncytial virus.Arumugham R.G., Seid R.C. Jr., Doyle S., Hildreth S.W., Paradisio P.R.J. Biol. Chem. 264:10339-10342(1989)
ncbi gi num :
9629206
ncbi acc num :
NP_056863.1
ncbi gb acc num :
NC_001781.1
uniprot acc num :
O36634
ncbi mol weight :
50.11kD
size1 :
0.05 mg (E-Coli)
price1 :
180 USD
size2 :
0.05 mg (Yeast)
price2 :
260
size3 :
0.1 mg (E-Coli)
price3 :
280
size4 :
0.1 mg (Yeast)
price4 :
375
size5 :
0.2 mg (E-Coli)
price5 :
490
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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