This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
IL-1beta Polyclonal Antibody
catalog :
MBS125139
quantity :
0.05 mL
price :
235 USD
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
application :
western blot, immunohistochemistry, immunocytochemistry
citations: 1
Reference
Fujita Y, Yago T, Matsumoto H, Asano T, Matsuoka N, Temmoku J, et al. Cold-inducible RNA-binding protein (CIRP) potentiates uric acid-induced IL-1β production. Arthritis Res Ther. 2021;23:128 pubmed publisher
product information
catalog number :
MBS125139
products type :
Antibody
products full name :
IL-1beta Polyclonal Antibody
products short name :
[IL-1beta]
products name syn :
[IL1B; IL-1beta ; IL-1b ; Interleukin-1 beta; IL-1 beta; Catabolin; IL1F2; IL1B]
other names :
[interleukin-1 beta proprotein; Interleukin-1 beta; interleukin-1 beta; IL-1 beta; catabolin; preinterleukin 1 beta; pro-interleukin-1-beta; interleukin 1, beta; Catabolin]
other gene names :
[IL1B; IL1B; IL-1; IL1F2; IL1-BETA; IL1F2; IL-1 beta]
uniprot entry name :
IL1B_HUMAN
clonality :
Polyclonal
isotype :
IgG
host :
Rabbit
reactivity :
Human, Zebrafish
purity :
Affinity purification
form :
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
storage stability :
Store at -20°C. Avoid freeze / thaw cycles
tested application :
Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
app notes :
Western Blot (WB): 1:100-1:200. Immunohistochemistry (IHC): 1:50-1: 100. Immunofluorescence (IF): 1:50-1:200
image1 heading :
Western Blot (WB)
other info1 :
Immunogen: Recombinant Protein of human IL1B
products description :
The protein encoded by the gene is a member of the interleukin 1 cytokine family. This cytokine is produced by activated macrophages as a proprotein, which is proteolytically processed to its active form by caspase 1 (CASP1/ICE). This cytcokine is an important mediator of the inflammatory response, and is involved in a variety of cellular activities, including cell proliferation, differentiation, and apoptosis. The induction of cyclooxygenase-2 (PTGS2/COX2) by this cytokine in the central nervous system (CNS) is found to contribute to the inflammatory pain hypersensitivity. This gene and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2.
products references :
1. Dinarello, C.A. (1998) Int. Rev. Immunol. 16, 457-499. 2. Burns, K. et al. (1998) J. Biol. Chem. 273, 12203-12209. 3. Cao, Z. et al. (1996) Nature 383, 443-446. 4. Cao, Z. et al. (1996) Science 271, 1128-1131. 5. Wesche, H. et al. (1997) Immunity 7, 837-847. 6. NinomiyaTsuji, J. et al. (1999) Nature 398, 252-256. 7. Thornberry, N. A. et al. (1992) Nature 356, 768-774. 8. Cerretti, D. P. et al. (1992) Science 256, 97-100. 9. Grahames, C.B. et al. (1999) Br J Pharmacol 127, 1915-21.
ncbi gi num :
10835145
ncbi acc num :
NP_000567.1
ncbi gb acc num :
NM_000576.2
uniprot acc num :
P01584
ncbi mol weight :
Calculated: 30 kDa; Observed: 36 kDa
ncbi pathways :
African Trypanosomiasis Pathway (194384); African Trypanosomiasis Pathway (194323); Alzheimer's Disease Pathway (83097); Alzheimer's Disease Pathway (509); Alzheimers Disease Pathway (672448); Amoebiasis Pathway (167324); Amoebiasis Pathway (167191); Apoptosis Pathway (83060); Apoptosis Pathway (470); Cellular Roles Of Anthrax Toxin Pathway (138076)
size1 :
0.05 mL
price1 :
235 USD
size2 :
0.1 mL
price2 :
350
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

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