product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Escherichia coli DNA helicase II (uvrD)
catalog :
MBS1216251
quantity :
0.01 mg (E-Coli)
price :
305 USD
more info or order :
product information
catalog number :
MBS1216251
products type :
Recombinant Protein
products full name :
Recombinant Escherichia coli DNA helicase II (uvrD)
products short name :
[DNA helicase II (uvrD)]
other names :
[DNA-dependent ATPase I and helicase II; DNA helicase II; DNA-dependent ATPase I and helicase II]
products gene name :
[uvrD]
other gene names :
[uvrD; uvrD; dar-2; dda; ECK3808; JW3786; mutU; pdeB; rad; recL; srjC; uvr502; uvrE; mutU; pdeB; rad; recL]
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
[1-720. Full length]
sequence length :
720
sequence :
MDVSYLLDSLNDKQREAVAAPRSNLLVLAGAGSGKTRVL
VHRIAWLMSVENCSPYSIMAVTFTNKAAAEMRHRIGQLM
GTSQGGMWVGTFHGLAHRLLRAHHMDANLPQDFQILDSE
DQLRLLKRLIKAMNLDEKQWPPRQAMWYINSQKDEGLRP
HHIQSYGNPVEQTWQKVYQAYQEACDRAGLVDFAELLLR
AHELWLNKPHILQHYRERFTNILVDEFQDTNNIQYAWIR
LLAGDTGKVMIVGDDDQSIYGWRGAQVENIQRFLNDFPG
AETIRLEQNYRSTSNILSAANALIENNNGRLGKKLWTDG
ADGEPISLYCAFNELDEARFVVNRIKTWQDNGGALAECA
ILYRSNAQSRVLEEALLQASMPYRIYGGMRFFERQEIKD
ALSYLRLIANRNDDAAFERVVNTPTRGIGDRTLDVVRQT
SRDRQLTLWQACRELLQEKALAGRAASALQRFMELIDAL
AQETADMPLHVQTDRVIKDSGLRTMYEQEKGEKGQTRIE
NLEELVTATRQFSYNEEDEDLMPLQAFLSHAALEAGEGQ
ADTWQDAVQLMTLHSAKGLEFPQVFIVGMEEGMFPSQMS
LDEGGRLEEERRLAYVGVTRAMQKLTLTYAETRRLYGKE
VYHRPSRFIGELPEECVEEVRLRATVSRPVSHQRMGTPM
VENDSGYKLGQRVRHAKFGEGTIVNMEGSGEHSRLQVAF
QGQGIKWLVAAYARLESV
purity :
Greater than 85% as determined by SDS-PAGE.
form :
Liquid containing glycerol
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Escherichia coli (strain K12)
other info2 :
Storage Buffer: Tris-based buffer, 50% glycerol
products description :
A helicase with DNA-dependent ATPase activity. Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand. Initiates unwinding more efficiently from a nicked substrate than ds duplex DNA. Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair, and probably also in repair of alkylated DNA
products references :
Determination of the initiation sites of transcription and translation of the uvrD gene of Escherichia coli." Yamamoto Y., Ogawa T., Shinagawa H., Nakayama T., Matsuo H., Ogawa H. J. Biochem. 99:1579-1590(1986)
ncbi gi num :
16131665
ncbi acc num :
NP_418258.1
ncbi gb acc num :
NC_000913.3
uniprot acc num :
P03018
ncbi mol weight :
82.0 kDa
ncbi pathways :
Mismatch Repair Pathway (1128); Mismatch Repair Pathway (453); Nucleotide Excision Repair Pathway (1127); Nucleotide Excision Repair Pathway (452)
ncbi summary :
The completion of nucleotide excision repair depends upon the release of the oligonucleotide fragment along with the UvrB and UvrC proteins which are then able to be recycled to undertake another excision repair event. [More information is available at EcoCyc: EG11064].
uniprot summary :
A helicase with DNA-dependent ATPase activity (PubMed:8419285). Unwinds DNA duplexes with 3' to 5' polarity with respect to the bound strand. Initiates unwinding more efficiently from a nicked substrate than ds duplex DNA (PubMed:8419285). Involved in the post-incision events of nucleotide excision repair and methyl-directed mismatch repair, and probably also in repair of alkylated DNA (Probable).
size1 :
0.01 mg (E-Coli)
price1 :
305 USD
size2 :
0.05 mg (E-Coli)
price2 :
375
size3 :
0.1 mg (E-Coli)
price3 :
545
size4 :
0.2 mg (E-Coli)
price4 :
800
size5 :
0.5 mg (E-Coli)
price5 :
1240
size6 :
1 mg (E-Coli)
price6 :
1840
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
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