catalog number :
MBS1215170
products type :
Recombinant Protein
products full name :
Recombinant Mouse Kinesin light chain 1 (Klc1)
products short name :
Kinesin light chain 1 (Klc1)
products name syn :
Kinesin light chain 1; KLC 1
other names :
Kinesin light chain 1; Kinesin light chain 1; kinesin light chain 1; KLC 1; kinesin 2 60/70kDa; kinesin light chain 1
products gene name :
Klc1
products gene name syn :
Klc1; Kns2
other gene names :
Klc1; Klc1; Kns2; AI874768; Kns2; KLC 1
uniprot entry name :
KLC1_MOUSE
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
1-541
sequence :
MYDNMSTMVY IKEEKLENVT QDEIISKTKQ VIQGLEALKN EHNSILQSLL ETLKCLKKDD ESNLVEEKSS MIRKSLEMLE LGLSEAQVMM ALSNHLNAVE SEKQNVRAQV RRLCQENQWL RDELANTQQK LQKSEQSVAQ LEEEKKHLEF MNQLKKYDDD ISPSEDKDSD SSKEPLDDLF PNDEDEPGQG IQHSDSSAAA ARQGYEIPAR LRTLHNLVIQ YASQGRYEVA VPSCKQALED LEKTSGHDHP DVATMLNILA LVYRDQNKYK DAANLLNDAL AIREKTLGRD HPAVAATLNN LAVLYGKRGK YKEAEPLCKR ALEIREKVLG KDHPDVAKQL NNLALLCQNQ GKYEEVEYYY QRALGIYQTK LGPDRTPNVA KTKNNLASCY LKQGKFKQAE TLYKEILTRA HEAEFGSVDD ENKPIWMHAE EREECKGKQK DGSAFGEYGG WYKACKVDSP TVTTTLKNLG ALYRRQGKFE AAETLEEAAM RSRKQGLDNV HKQRVAEVLN DPESMEKRRS RESLNMDVVK YESGPDGGEE A
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Mus musculus (Mouse)
products description :
Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity.
ncbi pathways :
Adaptive Immune System Pathway (971210); Factors Involved In Megakaryocyte Development And Platelet Production Pathway (1001326); Hemostasis Pathway (1001295); Immune System Pathway (971216); Kinesins Pathway (1001327); MHC Class II Antigen Presentation Pathway (1001204); Salmonella Infection Pathway (375174); Salmonella Infection Pathway (375149); XPodNet - Protein-protein Interactions In The Podocyte Expanded By STRING Pathway (755427)
ncbi summary :
Conventional kinesin is a tetrameric molecule composed of two heavy chains and two light chains, and transports various cargos along microtubules toward their plus ends. The heavy chains provide the motor activity, while the light chains bind to various cargos. This gene encodes a member of the kinesin light chain family. It associates with kinesin heavy chain through an N-terminal domain, and six tetratricopeptide repeat (TPR) motifs are thought to be involved in binding of cargos such as vesicles, mitochondria, and the Golgi complex. Thus, kinesin light chains function as adapter molecules and not motors per se. Although previously named "kinesin 2", this gene is not a member of the kinesin-2 / kinesin heavy chain subfamily of kinesin motor proteins. Extensive alternative splicing produces isoforms with different C-termini that are proposed to bind to different cargos; however, the full-length nature of some of these variants has not been determined. [provided by RefSeq, Jul 2008]
uniprot summary :
KLC1: a microtubule-associated force-producing protein that may play a role in organelle transport. The light chain may function in coupling of cargo to the heavy chain or in the modulation of its ATPase activity. Protein type: Microtubule-binding; Motor. Cellular Component: microtubule; neuron projection; cell; cytosol; ciliary rootlet; kinesin complex; growth cone; cytoskeleton; cell projection; cell soma; membrane; axon; cytoplasm; cytoplasmic vesicle; intracellular; vesicle. Molecular Function: tubulin binding; protein binding; microtubule motor activity. Biological Process: intracellular protein transport; axon cargo transport; microtubule-based movement
size2 :
0.05 mg (Baculovirus)
size4 :
0.05 mg (Mammalian-Cell)