product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human CRY1
catalog :
MBS120550
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3551C4a
reactivity :
human
application :
western blot
more info or order :
product information
catalog number :
MBS120550
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human CRY1
products short name :
CRY1
products name syn :
Homo sapiens cryptochrome 1 (photolyase-like) (CRY1), mRNA.Homo sapiens UTP18, small subunit (SSU) processome; PHLL1
other names :
Homo sapiens cryptochrome circadian clock 1 (CRY1), mRNA; Cryptochrome-1; cryptochrome-1; cryptochrome 1 (photolyase-like); cryptochrome circadian clock 1
products gene name :
CRY1
other gene names :
CRY1; CRY1; PHLL1
uniprot entry name :
CRY1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
3551C4a
host :
Mouse
reactivity :
Human
sequence length :
3310
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Blue light-dependent regulator of the circadian feedback loop. Inhibits CLOCK NPAS2-ARNTL E box-mediated transcription. Acts, in conjunction with CRY2, in maintaining period length and circadian rhythmicity. Has no photolyase activity. Capable of translocating circadian clock core proteins such as PER proteins to the nucleus. May inhibit CLOCK NPAS2-ARNTL transcriptional activity through stabilizing the unphosphorylated form of ARNTL[UniProtKB Function]
ncbi gi num :
401015115
ncbi acc num :
NP_004066.1
ncbi gb acc num :
NM_004075
ncbi mol weight :
66,395 Da
ncbi pathways :
BMAL1:CLOCK,NPAS2 Activates Circadian Gene Expression Pathway 477138!!Circadian Clock Pathway 187173!!Circadian Rhythm Pathway 83084!!Circadian Rhythm Pathway 495!!Diurnally Regulated Genes With Circadian Orthologs Pathway 198813
ncbi summary :
This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. Loss of the related gene in mouse results in a shortened circadian cycle in complete darkness. [provided by RefSeq, Jan 2014]
size :
0.1 mg
price :
345 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
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