catalog number :
MBS120545
products full name :
Mouse monoclonal antibody Anti-Human SOX6
products short name :
SOX6
products name syn :
Homo sapiens SRY (sex determining region Y)-box 6 (SOX6),; HSSOX6
other names :
Homo sapiens SRY (sex determining region Y)-box 6 (SOX6), transcript variant 2, mRNA; Transcription factor SOX-6; transcription factor SOX-6; SRY-box containing gene 6; SRY (sex determining region Y)-box 6
products gene name :
SOX6
other gene names :
SOX6; SOX6; SOXD; HSSOX6
uniprot entry name :
SOX6_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[NCBI Entrez Gene Summary]
ncbi acc num :
NP_201583.2
ncbi gb acc num :
NM_033326
ncbi mol weight :
88,988 Da
ncbi pathways :
Endochondral Ossification Pathway 198812
ncbi summary :
This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]