catalog number :
MBS120446
products full name :
Mouse monoclonal antibody Anti-Human BDP1
products short name :
BDP1
products name syn :
Homo sapiens B double prime 1, subunit of RNA polymeraseIII transcription initiation factor IIIB (BDP1), mRNA. ; TFC5; TFNR; TAF3B1;KIAA1241; KIAA1689;TFIIIB90; HSA238520;TFIIIB150; DKFZp686K0831;DKFZp686C01233
other names :
Homo sapiens B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB (BDP1), mRNA; Transcription factor TFIIIB component B'' homolog; transcription factor TFIIIB component B'' homolog; RNA polymerase III transcription initiation factor B''; TATA box binding protein (TBP)-associated factor, RNA polymerase III, GTF3B subunit 1; transcription factor IIIB 150; transcription factor-like nuclear regulator; B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB; Transcription factor IIIB 150; TFIIIB150; Transcription factor-like nuclear regulator
products gene name :
BDP1
other gene names :
BDP1; BDP1; TFC5; TFNR; TAF3B1; TFIIIB''; TFIIIB90; HSA238520; TFIIIB150
uniprot entry name :
BDP1_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription.[NCBI Entrez Gene Summary]
ncbi acc num :
NP_060899.2
ncbi gb acc num :
NM_018429
ncbi mol weight :
51,420 Da
ncbi pathways :
Gene Expression Pathway 105937!!RNA Polymerase I, RNA Polymerase III, And Mitochondrial Transcription Pathway 160948!!RNA Polymerase III Abortive And Retractive Initiation Pathway 160949!!RNA Polymerase III Transcription Pathway 106561!!RNA Polymerase III Transcription Initiation Pathway 106562!!RNA Polymerase III Transcription Initiation From Type 1 Promoter Pathway 106563!!RNA Polymerase III Transcription Initiation From Type 2 Promoter Pathway 106564!!RNA Polymerase III Transcription Initiation From Type 3 Promoter Pathway 106565
ncbi summary :
The product of this gene is a subunit of the TFIIIB transcription initiation complex, which recruits RNA polymerase III to target promoters in order to initiate transcription. The encoded protein localizes to concentrated aggregates in the nucleus, and is required for transcription from all three types of polymerase III promoters. It is phosphorylated by casein kinase II during mitosis, resulting in its release from chromatin and suppression of polymerase III transcription. [provided by RefSeq, Jul 2008]