product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human TUPLE1
catalog :
MBS120439
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
374C6a
reactivity :
human
application :
immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120439
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human TUPLE1
products short name :
TUPLE1
products name syn :
H.sapiens TUP1-like enhancer of split gene 1 (TUPLE1) mRNA.
other names :
H.sapiens TUP1-like enhancer of split gene 1 (TUPLE1) mRNA; Protein HIRA; protein HIRA; DiGeorge critical region gene 1; HIR histone cell cycle regulation defective homolog A; TUP1-like enhancer of split protein 1; histone cell cycle regulator; TUP1-like enhancer of split protein 1
products gene name :
TUPLE1
other gene names :
HIRA; HIRA; TUP1; DGCR1; TUPLE1
uniprot entry name :
HIRA_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
374C6a
host :
Mouse
reactivity :
Human
sequence length :
3420
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene encodes a histone chaperone that preferentially places the variant histone
ncbi gi num :
434982
ncbi acc num :
CAA53044.1
uniprot acc num :
P54198
ncbi mol weight :
89,299 Da
ncbi pathways :
Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!DNA Damage/Telomere Stress Induced Senescence Pathway 905994!!Formation Of Senescence-Associated Heterochromatin Foci (SAHF) Pathway 905995
ncbi summary :
This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
size :
0.1 mg
price :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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