catalog number :
MBS1204354
products type :
Recombinant Protein
products full name :
Recombinant Human Keratin, type I cuticular Ha8
products short name :
Keratin, type I cuticular Ha8
products name syn :
Hair keratin, type I Ha8; Keratin-38; K38
other names :
keratin, type I cuticular Ha8; Keratin, type I cuticular Ha8; keratin, type I cuticular Ha8; keratin 38, type I; Hair keratin, type I Ha8; Keratin-38; K38
products gene name :
KRT38
other gene names :
KRT38; KRT38; HA8; hHa8; KRTHA8; HHA8; HKA8; KRTHA8; K38
uniprot entry name :
KRT38_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
2-456
sequence :
TSSYSSSSCPLGCTMAPGARNVSVSPIDIGCQPGAEANI
APMCLLANVAHANRVRVGSTPLGRPSLCLPPTCHTACPL
PGTCHIPGNIGICGAYGENTLNGHEKETMQFLNDRLANY
LEKVRQLEQENAELEATLLERSKCHESTVCPDYQSYFHT
IEELQQKILCSKAENARLIVQIDNAKLAADDFRIKLESE
RSLRQLVEADKCGTQKLLDDATLAKADLEAQQESLKEEQ
LSLKSNHEQEVKILRSQLGEK
purity :
Greater than 90% as determined by SDS-PAGE.
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degree C, for extended storage, conserve at -20 degree C or -80 degree C.
products categories :
Signal Transduction
products references :
Characterization of a 190-kilobase pair domain of human type I hair keratin genes.Rogers M.A., Winter H., Wolf C., Heck M., Schweizer J.J. Biol. Chem. 273:26683-26691(1998)
Schweizer J.DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.Zody M.C., Garber M., Adams D.J., Sharpe T., Harrow J., Lupski J.R., Nicholson C., Searle S.M., Wilming L., Young S.K., Abouelleil A., Allen N.R., Bi W., Bloom T., Borowsky M.L., Bugalter B.E., Butler J., Chang J.L., Chen C.-K., Cook A., Corum B., Cuomo C.A., de Jong P.J., DeCaprio D., Dewar K., FitzGerald M., Gilbert J., Gibson R., Gnerre S., Goldstein S., Grafham D.V., Grocock R., Hafez N., Hagopian D.S., Hart E., Norman C.H., Humphray S., Jaffe D.B., Jones M., Kamal M., Khodiyar V.K., LaButti K., Laird G., Lehoczky J., Liu X., Lokyitsang T., Loveland J., Lui A., Macdonald P., Major J.E., Matthews L., Mauceli E., McCarroll S.A., Mihalev A.H., Mudge J., Nguyen C., Nicol R., O'Leary S.B., Osoegawa K., Schwartz D.C., Shaw-Smith C., Stankiewicz P., Steward C., Swarbreck D., Venkataraman V., Whittaker C.A., Yang X., Zimmer A.R., Bradley A., Hubbard T., Birren B.W., Rogers J., Lander E.S., Nusbaum C.Nature 440:1045-1049(2006)
ncbi acc num :
NP_006762.3
ncbi gb acc num :
NM_006771.3
ncbi summary :
The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]
uniprot summary :
KRT38: Belongs to the intermediate filament family. Protein type: Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 17q21.2. Cellular Component: intermediate filament. Molecular Function: protein binding; structural molecule activity
size5 :
0.05 mg (Baculovirus)