This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human CDKN1B
catalog :
MBS120394
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2144C8a
reactivity :
human
application :
western blot
product information
catalog number :
MBS120394
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human CDKN1B
products short name :
CDKN1B
products name syn :
Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B), mRNA.; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
other names :
Homo sapiens cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B), mRNA; Cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B; cyclin-dependent kinase inhibitor 1B (p27, Kip1); Cyclin-dependent kinase inhibitor p27; p27Kip1
products gene name :
CDKN1B
other gene names :
CDKN1B; CDKN1B; KIP1; MEN4; CDKN4; MEN1B; P27KIP1
uniprot entry name :
CDN1B_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2144C8a
host :
Mouse
reactivity :
Human
sequence length :
2535
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.[NCBI Entrez Gene Summary]
ncbi gi num :
584458479
ncbi acc num :
NP_004055.1
ncbi gb acc num :
NM_004064
ncbi mol weight :
22,073 Da
ncbi pathways :
AKT Phosphorylates Targets In The Cytosol Pathway 106475!!Adaptive Immune System Pathway 366160!!AhR Pathway 755436!!C-MYB Transcription Factor Network Pathway 138073!!Cell Cycle Pathway 530733!!Cell Cycle Checkpoints Pathway 105739!!Cell Cycle, Mitotic Pathway 105765!!Cell Cycle Pathway 198811!!Cell Cycle Pathway 83054!!Cell Cycle Pathway 463
ncbi summary :
This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. Mutations in this gene are associated with multiple endocrine neoplasia type IV (MEN4). [provided by RefSeq, Apr 2014]
size :
0.1 mg
price :
345 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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