product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human ORC6L
catalog :
MBS120389
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2679C2b
reactivity :
human
application :
immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120389
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human ORC6L
products short name :
ORC6L
products name syn :
Homo sapiens origin recognition complex, subunit 6 like (yeast) (ORC6L), mRNA.; ORC6
other names :
Homo sapiens origin recognition complex, subunit 6 (ORC6), transcript variant 1, mRNA; Origin recognition complex subunit 6; origin recognition complex subunit 6; origin recognition complex, subunit 6
products gene name :
ORC6L
other gene names :
ORC6; ORC6; ORC6L
uniprot entry name :
ORC6_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2679C2b
host :
Mouse
reactivity :
Human
sequence length :
1644
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. It has been shown that this protein and and ORC1L are loosely associated with the core complex consisting of ORC2L, -3L, -4L and -5L. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [NCBI Entrez Gene Summary]
ncbi gi num :
313661351
ncbi acc num :
NP_055136.1
ncbi gb acc num :
NM_014321
ncbi mol weight :
28,107 Da
ncbi pathways :
Activation Of ATR In Response To Replication Stress Pathway 105754!!Activation Of The Pre-replicative Complex Pathway 105777!!Assembly Of The ORC Complex At The Origin Of Replication Pathway 105822!!Assembly Of The Pre-replicative Complex Pathway 105821!!CDC6 Association With The ORC:origin Complex Pathway 105823!!CDT1 Association With The CDC6:ORC:origin Complex Pathway 105824!!Cell Cycle Pathway 530733!!Cell Cycle Checkpoints Pathway 105739!!Cell Cycle, Mitotic Pathway 105765!!Cell Cycle Pathway 198811
ncbi summary :
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]
size :
0.1 mg
price :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!