product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human HTATIP
catalog :
MBS120385
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2455C3a
reactivity :
human
application :
immunocytochemistry
more info or order :
product information
catalog number :
MBS120385
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human HTATIP
products short name :
HTATIP
products name syn :
Homo sapiens HIV-1 Tat interacting protein, 60kDa (HTATIP), transcript variant 1, mRNA.; TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP1
other names :
Homo sapiens K(lysine) acetyltransferase 5 (KAT5), transcript variant 1, mRNA; Histone acetyltransferase KAT5; histone acetyltransferase KAT5; 60 kDa Tat-interactive protein; HIV-1 Tat interactive protein, 60kDa; K-acetyltransferase 5; Tat interacting protein, 60kDa; cPLA(2)-interacting protein; cPLA2 interacting protein; histone acetyltransferase HTATIP; K(lysine) acetyltransferase 5; 60 kDa Tat-interactive protein; Tip60; Histone acetyltransferase HTATIP; HIV-1 Tat interactive protein; Lysine acetyltransferase 5; cPLA(2)-interacting protein
products gene name :
HTATIP
other gene names :
KAT5; KAT5; TIP; ESA1; PLIP; TIP60; cPLA2; HTATIP; ZC2HC5; HTATIP1
uniprot entry name :
KAT5_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2455C3a
host :
Mouse
reactivity :
Human
sequence length :
2347
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [NCBI Entrez Gene Summary]
ncbi gi num :
332205929
ncbi acc num :
NP_874369.1
ncbi gb acc num :
NM_182710
ncbi mol weight :
56,292 Da
ncbi pathways :
ATF-2 Transcription Factor Network Pathway (138006); Androgen Receptor Signaling Pathway (198806); C-MYC Pathway (169344); Chromatin Modifying Enzymes Pathway (1127682); Chromatin Organization Pathway (1127681); Disease Pathway (530764); HATs Acetylate Histones Pathway (1127683); HTLV-I Infection Pathway (373901); HTLV-I Infection Pathway (373889); IL-9 Signaling Pathway (198883)
ncbi summary :
The protein encoded by this gene belongs to the MYST family of histone acetyl transferases (HATs) and was originally isolated as an HIV-1 TAT-interactive protein. HATs play important roles in regulating chromatin remodeling, transcription and other nuclear processes by acetylating histone and nonhistone proteins. This protein is a histone acetylase that has a role in DNA repair and apoptosis and is thought to play an important role in signal transduction. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
uniprot summary :
Tip60: a histone acetyl transferase (HAT) of the MYST family. Originally isolated as an HIV-1 TAT-interactive protein. Plays an important role in regulating chromatin remodeling, transcription and other nuclear processes by acetylating nuclear proteins. Plays a role in DNA repair and apoptosis. Three splice variants have been described. Protein type: EC 2.3.1.48; Nucleolus; Nuclear receptor co-regulator; Acetyltransferase. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: nucleoplasm; transcription factor complex; NuA4 histone acetyltransferase complex; perinuclear region of cytoplasm; nucleolus; nucleus; cytosol. Molecular Function: protein binding; histone acetyltransferase activity; androgen receptor binding; metal ion binding; transcription coactivator activity; protein complex binding. Biological Process: proteasomal ubiquitin-dependent protein catabolic process; establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; viral reproduction; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of interleukin-2 production; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; regulation of growth; double-strand break repair; androgen receptor signaling pathway; positive regulation of transcription from RNA polymerase II promoter; histone acetylation; response to ionizing radiation; negative regulation of transcription, DNA-dependent
size1 :
0.1 mg
price1 :
345 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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