catalog number :
MBS120383
products full name :
Mouse monoclonal antibody Anti-Human ARID4A
products short name :
ARID4A
products name syn :
Homo sapiens AT rich interactive domain 4A (RBP1-like) (ARID4A), transcript variant 1, mRNA.; RBP1; RBBP1; RBP-1
other names :
Homo sapiens AT rich interactive domain 4A (RBP1-like) (ARID4A), transcript variant 1, mRNA; AT-rich interactive domain-containing protein 4A; AT-rich interactive domain-containing protein 4A; ARID domain-containing protein 4A; retinoblastoma binding protein 1; retinoblastoma-binding protein 1; AT rich interactive domain 4A (RBP1-like); Retinoblastoma-binding protein 1; RBBP-1
products gene name :
ARID4A
other gene names :
ARID4A; ARID4A; RBP1; RBBP1; RBP-1; RBBP-1
uniprot entry name :
ARI4A_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. [NCBI Entrez Gene Summary]
ncbi acc num :
NP_002883.3
ncbi gb acc num :
NM_002892
ncbi mol weight :
134,951 Da
ncbi pathways :
Chromatin Modifying Enzymes Pathway 1127682!!Chromatin Organization Pathway 1127681!!HDACs Deacetylate Histones Pathway 1127684
ncbi summary :
The protein encoded by this gene is a ubiquitously expressed nuclear protein. It binds directly, with several other proteins, to retinoblastoma protein (pRB) which regulates cell proliferation. pRB represses transcription by recruiting the encoded protein. This protein, in turn, serves as a bridging molecule to recruit HDACs and, in addition, provides a second HDAC-independent repression function. The encoded protein possesses transcriptional repression activity. Multiple alternatively spliced transcripts have been observed for this gene, although not all transcript variants have been fully described. [provided by RefSeq, Jul 2008]