catalog number :
MBS120379
products full name :
Mouse monoclonal antibody Anti-Human APRIN
products short name :
APRIN
products name syn :
Homo sapiens PDS5, regulator of cohesion maintenance, homolog B (S.cerevisiae) (PDS5B), mRNA.; AS3; APRIN; CG008; FLJ23236; KIAA0979; RP1-267P19.1
other names :
Homo sapiens PDS5 cohesin associated factor B (PDS5B), mRNA; Sister chromatid cohesion protein PDS5 homolog B; sister chromatid cohesion protein PDS5 homolog B; androgen induced inhibitor of proliferation; androgen-induced proliferation inhibitor; androgen-induced prostate proliferative shutoff-associated protein AS3; androgen-induced shutoff 3; PDS5 cohesin associated factor B; Androgen-induced proliferation inhibitor; Androgen-induced prostate proliferative shutoff-associated protein AS3
products gene name :
APRIN
other gene names :
PDS5B; PDS5B; AS3; APRIN; CG008
uniprot entry name :
PDS5B_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Plays a role in androgen-induced proliferative arrest in prostate cells. Required for maintenance of sister chromatid cohesion during mitosis. [UniProtKB Function]
ncbi acc num :
NP_055847.1
ncbi gb acc num :
NM_015032
ncbi mol weight :
14,281 Da
ncbi pathways :
Cell Cycle Pathway 530733!!Cell Cycle, Mitotic Pathway 105765!!Cohesin Loading Onto Chromatin Pathway 730319!!Establishment Of Sister Chromatid Cohesion Pathway 730313!!M Phase Pathway 105812!!Mitotic Anaphase Pathway 105818!!Mitotic Metaphase And Anaphase Pathway 730317!!Mitotic Prometaphase Pathway 105815!!Mitotic Telophase/Cytokinesis Pathway 105819!!Resolution Of Sister Chromatid Cohesion Pathway 730315
ncbi summary :
This gene encodes a protein that interacts with the conserved protein complex termed cohesion. The cohesion complex holds together sister chromatids and facilitates accurate chromosome segregation during mitosis and meiosis. This protein is also a negative regulator of cell proliferation and may be a tumor-suppressor gene. [provided by RefSeq, May 2010]