catalog number :
MBS120373
products full name :
Mouse monoclonal antibody Anti-Human FBXO18
products short name :
FBXO18
products name syn :
Homo sapiens F-box protein, helicase, 18 (FBXO18), transcript variant 1; FBH1; Fbx18; FLJ14590; MGC131916; MGC141935; MGC141937
other names :
Homo sapiens F-box protein, helicase, 18 (FBXO18), transcript variant 1, mRNA; F-box only protein 18; F-box only protein 18; F-box DNA helicase 1; F-box only protein, helicase, 18; F-box protein, helicase, 18; F-box DNA helicase 1
products gene name :
FBXO18
other gene names :
FBXO18; FBXO18; FBH1; Fbx18
uniprot entry name :
FBX18_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [NCBI Entrez Gene Summary]
ncbi acc num :
NP_116196.3
ncbi gb acc num :
NM_032807
ncbi mol weight :
123,375 Da
ncbi summary :
This gene encodes a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbx class. It contains an F-box motif and seven conserved helicase motifs, and has both DNA-dependent ATPase and DNA unwinding activities. Alternatively spliced transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]