catalog number :
MBS120363
products full name :
Mouse monoclonal antibody Anti-Human NEIL2
products short name :
NEIL2
products name syn :
Homo sapiens nei like 2 (E. coli) ; NEH2; MGC2832; MGC4505; FLJ31644
other names :
Homo sapiens nei endonuclease VIII-like 2 (E. coli) (NEIL2), transcript variant 1, mRNA; Endonuclease 8-like 2; endonuclease 8-like 2; DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; endonuclease VIII-like 2; nei homolog 2; nei like 2; nei-like protein 2; nei endonuclease VIII-like 2 (E. coli); DNA glycosylase/AP lyase Neil2; DNA-(apurinic or apyrimidinic site) lyase Neil2; Endonuclease VIII-like 2; Nei homolog 2; NEH2; Nei-like protein 2
products gene name :
NEIL2
other gene names :
NEIL2; NEIL2; NEH2; NEI2
uniprot entry name :
NEIL2_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002).[supplied by OMIM] [NCBI Entrez Gene Summary]
ncbi acc num :
NP_659480.1
ncbi gb acc num :
NM_145043
ncbi mol weight :
24,136 Da
ncbi pathways :
Base Excision Repair Pathway 83043!!Base Excision Repair Pathway 451
ncbi summary :
NEIL2 belongs to a class of DNA glycosylases homologous to the bacterial Fpg/Nei family. These glycosylases initiate the first step in base excision repair by cleaving bases damaged by reactive oxygen species and introducing a DNA strand break via the associated lyase reaction (Bandaru et al., 2002 [PubMed 12509226])[supplied by OMIM, Mar 2008]