product summary
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company name :
MyBioSource
product type :
protein
product name :
Recombinant Human Interleukin-18-binding protein (IL18BP)
catalog :
MBS1203461
quantity :
0.5 mg (E-Coli)
price :
905 USD
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS1203461
products type :
Recombinant Protein
products full name :
Recombinant Human Interleukin-18-binding protein (IL18BP)
products short name :
Interleukin-18-binding protein (IL18BP)
products name syn :
Interleukin-18-binding protein; IL-18BP; Tadekinig-alfa
other names :
interleukin-18-binding protein isoform a; Interleukin-18-binding protein; interleukin-18-binding protein; IL-18BP; tadekinig-alfa; MC51L-53L-54L homolog gene product; interleukin 18 binding protein; Tadekinig-alfa
products gene name :
IL18BP
other gene names :
IL18BP; IL18BP; IL18BPa; IL-18BP
uniprot entry name :
I18BP_HUMAN
host :
E Coli or Yeast or Baculovirus or Mammalian Cell
sequence positions :
31-194
sequence length :
164
sequence :
TPVSQTTTAA TASVRSTKDP CPSQPPVFPA AKQCPALEVT WPEVEVPLNG TLSLSCVACS RFPNFSILYW LGNGSFIEHL PGRLWEGSTS RERGSTGTQL CKALVLEQLT PALHSTNFSC VLVDPEQVVQ RHVVLAQLWA GLRATLPPTQ EALPSSHSSP QQQG
purity :
>90%
form :
Liquid containing glycerol; lyophilization may be available upon request.
storage stability :
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
other info1 :
Species: Homo sapiens (Human)
ncbi gi num :
89111125
ncbi acc num :
NP_001034748.1
ncbi gb acc num :
NM_001039659.1
uniprot acc num :
O95998
ncbi mol weight :
17,478 Da
ncbi summary :
The protein encoded by this gene functions as an inhibitor of the proinflammatory cytokine, IL18. It binds IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production, resulting in reduced T-helper type 1 immune responses. This protein is constitutively expressed and secreted in mononuclear cells. Elevated level of this protein is detected in the intestinal tissues of patients with Crohn's disease. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Feb 2011]
uniprot summary :
IL18BP: Isoform A binds to IL-18 and inhibits its activity. Functions as an inhibitor of the early TH1 cytokine response. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Secreted; Secreted, signal peptide. Chromosomal Location of Human Ortholog: 11q13. Cellular Component: extracellular space; extracellular region. Molecular Function: receptor antagonist activity; interleukin-18 binding. Biological Process: T-helper 1 type immune response; response to lipopolysaccharide
size1 :
0.5 mg (E-Coli)
price1 :
905 USD
size2 :
0.05 mg (Baculovirus)
price2 :
905
size3 :
0.5 mg (Yeast)
price3 :
1130
size4 :
0.05 mg (Mammalian-Cell)
price4 :
1130
size5 :
1 mg (E-Coli)
price5 :
1340
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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