product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human HOXA5
catalog :
MBS120329
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
129C1a
reactivity :
human
application :
immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120329
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human HOXA5
products short name :
HOXA5
products name syn :
Homo sapiens homeobox A5; HOX1.3; MGC9376
other names :
Homo sapiens homeobox A5, mRNA; Homeobox protein Hox-A5; homeobox protein Hox-A5; homeo box 1C; homeo box A5; homeobox protein HOXA5; homeobox protein Hox-1C; homeobox A5; Homeobox protein Hox-1C
products gene name :
HOXA5
other gene names :
HOXA5; HOXA5; HOX1; HOX1C; HOX1.3
uniprot entry name :
HXA5_HUMAN
clonality :
Monoclonal
isotype :
IgG2a
clone :
129C1a
host :
Mouse
reactivity :
Human
sequence length :
1160
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [NCBI Entrez Gene Summary]
ncbi gi num :
15489146
ncbi acc num :
BC013682
ncbi mol weight :
29,345 Da
ncbi summary :
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. Methylation of this gene may result in the loss of its expression and, since the encoded protein upregulates the tumor suppressor p53, this protein may play an important role in tumorigenesis. [provided by RefSeq, Jul 2008]
uniprot summary :
HOXA5: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Also binds to its own promoter. Binds specifically to the motif 5 -CYYNATTA[TG]Y-3 . Belongs to the Antp homeobox family. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 7p15.2. Cellular Component: nucleus. Molecular Function: protein binding; DNA binding; transcription factor activity. Biological Process: cell migration; negative regulation of erythrocyte differentiation; positive regulation of myeloid cell differentiation; transcription, DNA-dependent; positive regulation of apoptosis; multicellular organism growth; embryonic skeletal morphogenesis; anterior/posterior pattern formation; regulation of mammary gland epithelial cell proliferation; respiratory system process; negative regulation of angiogenesis; thyroid gland development; positive regulation of transcription from RNA polymerase II promoter; alveolus development
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!