catalog number :
MBS120317
products full name :
Mouse monoclonal antibody Anti-Human JMJD2A
products short name :
JMJD2A
products name syn :
omo sapiens jumonji domain containing 2A; KIAA0677; JHDM3A
other names :
Homo sapiens jumonji domain containing 2A, mRNA; Lysine-specific demethylase 4A; lysine-specific demethylase 4A; jmjC domain-containing histone demethylation protein 3A; jumonji C domain-containing histone demethylase 3A; jumonji domain containing 2; jumonji domain containing 2A; jumonji domain-containing protein 2A; tudor domain containing 14A; lysine (K)-specific demethylase 4A; JmjC domain-containing histone demethylation protein 3A; Jumonji domain-containing protein 2A
products gene name :
JMJD2A
other gene names :
KDM4A; KDM4A; JMJD2; JHDM3A; JMJD2A; TDRD14A
uniprot entry name :
KDM4A_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein with a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [NCBI Entrez Gene Summary]
ncbi mol weight :
54,697 Da
ncbi pathways :
Chromatin Modifying Enzymes Pathway 1127682!!Chromatin Organization Pathway 1127681!!HDMs Demethylate Histones Pathway 1127685
ncbi summary :
This gene is a member of the Jumonji domain 2 (JMJD2) family and encodes a protein containing a JmjN domain, a JmjC domain, a JD2H domain, two TUDOR domains, and two PHD-type zinc fingers. This nuclear protein functions as a trimethylation-specific demethylase, converting specific trimethylated histone residues to the dimethylated form, and as a transcriptional repressor. [provided by RefSeq, Apr 2009]