product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human TEAD2
catalog :
MBS120313
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
404C5a
reactivity :
human
application :
immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120313
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human TEAD2
products short name :
TEAD2
products name syn :
Homo sapiens TEA domain family member 2; ETF; TEF4;TEF-4
other names :
Homo sapiens TEA domain family member 2 (TEAD2), transcript variant 5, mRNA; Transcriptional enhancer factor TEF-4; transcriptional enhancer factor TEF-4; TEA domain family member 2; TEA domain family member 2; TEAD-2
products gene name :
TEAD2
other gene names :
TEAD2; TEAD2; ETF; TEF4; TEF-4; TEAD-2
uniprot entry name :
TEAD2_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
404C5a
host :
Mouse
reactivity :
Human
sequence length :
2220
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Putative transcription factor that binds to the SPH and GT-IIC "enhansons" (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif (By similarity). [UniProtKB Function]
ncbi gi num :
20070102
ncbi acc num :
NP_003589.1
ncbi gb acc num :
NM_003598
ncbi mol weight :
49,640 Da
ncbi pathways :
Fatty Acid, Triacylglycerol, And Ketone Body Metabolism Pathway (160977); Gene Expression Pathway (105937); Generic Transcription Pathway (105938); Hippo Signaling Pathway (1084759); Hippo Signaling Pathway (1108222); Hippo Signaling Pathway (749777); Hippo Signaling Pathway (750388); Metabolism Pathway (477135); Metabolism Of Lipids And Lipoproteins Pathway (160976); PPARA Activates Gene Expression Pathway (530749)
uniprot summary :
TEAD2: Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC enhansons (5 - GTGGAATGT-3 ). May be involved in the gene regulation of neural development. Binds to the M-CAT motif. Interacts with YAP1 and WWTR1/TAZ. Protein type: DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 19q13.3. Cellular Component: nucleoplasm; transcription factor complex; nucleus. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; DNA binding; transcription factor activity. Biological Process: paraxial mesoderm development; transcription initiation from RNA polymerase II promoter; regulation of transcription, DNA-dependent; lateral mesoderm development; neural tube closure; gene expression; positive regulation of transcription from RNA polymerase II promoter; notochord development; vasculogenesis
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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