catalog number :
MBS120311
products full name :
Mouse monoclonal antibody Anti-Human UBP1
products short name :
UBP1
products name syn :
Homo sapiens upstream binding protein 1 (LBP-1a) ; LBP1A; LBP1B; LBP-1B; LBP-1a; DKFZp686L1745
other names :
Homo sapiens upstream binding protein 1 (LBP-1a) (UBP1), transcript variant 1, mRNA; Upstream-binding protein 1; upstream-binding protein 1; transcription factor LBP-1; upstream binding protein 1 (LBP-1a); Transcription factor LBP-1
products gene name :
UBP1
other gene names :
UBP1; UBP1; LBP1A; LBP1B; LBP-1B; LBP-1a
uniprot entry name :
UBIP1_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Functions as a transcriptional activator in a promoter context-dependent manner. Modulates the placental expression of CYP11A1. Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Involved in regulation of the alpha-globin gene in erythroid cells. Activation of the alpha-globin promoter in erythroid cells is via synergistic interaction with TFCP2 (By similarity). Binds strongly to sequences around the HIV-1 initiation site and weakly over the TATA-box. Represses HIV-1 transcription by inhibiting the binding of TFIID to the TATA-box. [UniProtKB Function]
ncbi acc num :
NP_055332.3
ncbi gb acc num :
NM_014517
ncbi mol weight :
56,453 Da