catalog number :
MBS120303
products full name :
Mouse monoclonal antibody Anti-Human NFE2L2
products short name :
NFE2L2
products name syn :
Homo sapiens nuclear factor (erythroid-derived 2)-like 2 ; NRF2
other names :
Homo sapiens nuclear factor, erythroid 2-like 2 (NFE2L2), transcript variant 1, mRNA; Nuclear factor erythroid 2-related factor 2; nuclear factor erythroid 2-related factor 2; HEBP1; NF-E2-related factor 2; NFE2-related factor 2; nuclear factor (erythroid-derived 2)-like 2; nuclear factor erythroid-derived 2-like 2; nuclear factor, erythroid derived 2, like 2; nuclear factor, erythroid 2-like 2; HEBP1; Nuclear factor, erythroid derived 2, like 2
products gene name :
NFE2L2
other gene names :
NFE2L2; NFE2L2; NRF2
uniprot entry name :
NF2L2_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
NFE2 (MIM 601490), NFE2L1 (MIM 163260), and NFE2L2 comprise a family of human genes encoding basic leucine zipper (bZIP) transcription factors. They share highly conserved regions that are distinct from other bZIP families, such as JUN (MIM 165160) and FOS (MIM 164810), although remaining regions have diverged considerably from each other (Chan et al., 1995).[supplied by OMIM] [NCBI Entrez Gene Summary]
ncbi acc num :
NP_006155.2
ncbi gb acc num :
NM_006164
ncbi mol weight :
65,356 Da
ncbi pathways :
AhR Pathway 755436!!Keap1-Nrf2 Pathway 198777!!Oxidative Stress Pathway 198916!!Protein Processing In Endoplasmic Reticulum Pathway 167325!!Protein Processing In Endoplasmic Reticulum Pathway 167190!!Selenium Metabolism And Selenoproteins Pathway 198846
ncbi summary :
This gene encodes a transcription factor which is a member of a small family of basic leucine zipper (bZIP) proteins. The encoded transcription factor regulates genes which contain antioxidant response elements (ARE) in their promoters; many of these genes encode proteins involved in response to injury and inflammation which includes the production of free radicals. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]