catalog number :
MBS120299
products full name :
Mouse monoclonal antibody Anti-Human ZNF384
products short name :
ZNF384
products name syn :
Homo sapiens zinc finger protein 384; NP; CIZ; CAGH1A; CAGH1; NMP4; ERDA2
other names :
Homo sapiens zinc finger protein 384, mRNA; Zinc finger protein 384; zinc finger protein 384; CAG repeat protein 1; Cas-interacting zinc finger protein; expanded repeat domain, CAG/CTG 2; nuclear matrix transcription factor 4; trinucleotide repeat-containing gene 1 protein; zinc finger protein 384; CAG repeat protein 1; CAS-interacting zinc finger protein; Nuclear matrix transcription factor 4; Nuclear matrix protein 4; Trinucleotide repeat-containing gene 1 protein
products gene name :
ZNF384
other gene names :
ZNF384; ZNF384; NP; CIZ; NMP4; CAGH1; ERDA2; TNRC1; CAGH1A
uniprot entry name :
ZN384_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene contains long CAG trinucleotide repeats coding consecutive glutamine residues. The gene product may functions as a transcription factor, with a potential role in the regulation of neurodevelopment or neuroplasticity. The protein appears to bind and regulate the promoters of MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Multiple transcript variants encoding several isoforms have been found for this gene. [NCBI Entrez Gene Summary]
ncbi mol weight :
50,538 Da
ncbi summary :
This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]