catalog number :
MBS120298
products full name :
Mouse monoclonal antibody Anti-Human HEYL
products short name :
HEYL
products name syn :
Homo sapiens hairy/enhancer-of-split related with YRPW motif-like; HRT3; MGC12623
other names :
Homo sapiens hes-related family bHLH transcription factor with YRPW motif-like (HEYL), mRNA; Hairy/enhancer-of-split related with YRPW motif-like protein; hairy/enhancer-of-split related with YRPW motif-like protein; HEY-like protein; HRT-3; class B basic helix-loop-helix protein 33; hHRT3; hHeyL; hairy-related transcription factor 3; hairy/enhancer-of-split related with YRPW motif 3; hes-related family bHLH transcription factor with YRPW motif-like; Class B basic helix-loop-helix protein 33; bHLHb33; Hairy-related transcription factor 3; HRT-3; hHRT3
products gene name :
HEYL
other gene names :
HEYL; HEYL; HEY3; HRT3; HESR3; bHLHb33
uniprot entry name :
HEYL_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [NCBI Entrez Gene Summary]
ncbi acc num :
NP_055386.1
ncbi gb acc num :
NM_014571
ncbi mol weight :
35,087 Da
ncbi pathways :
Constitutive Signaling By NOTCH1 HD+PEST Domain Mutants Pathway 771595!!Constitutive Signaling By NOTCH1 PEST Domain Mutants Pathway 771593!!Disease Pathway 530764!!FBXW7 Mutants And NOTCH1 In Cancer Pathway 771596!!NOTCH1 Intracellular Domain Regulates Transcription Pathway 576271!!Signal Transduction Pathway 477114!!Signaling By NOTCH Pathway 106485!!Signaling By NOTCH1 Pathway 576269!!Signaling By NOTCH1 HD Domain Mutants In Cancer Pathway 771590!!Signaling By NOTCH1 HD+PEST Domain Mutants In Cancer Pathway 771594
ncbi summary :
This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]