catalog number :
MBS120279
products full name :
Mouse monoclonal antibody Anti-Human AHCTF1
products short name :
AHCTF1
products name syn :
Homo sapiens AT hook containing transcription factor 1 (AHCTF1); ELYS; MST108; TMBS62; MSTP108; DKFZp434N093
other names :
Homo sapiens AT hook containing transcription factor 1 (AHCTF1), mRNA; Protein ELYS; protein ELYS; ELYS transcription factor like protein TMBS62; ELYS transcription factor-like protein TMBS62; embryonic large molecule derived from yolk sac; putative AT-hook-containing transcription factor 1; AT hook containing transcription factor 1; Embryonic large molecule derived from yolk sac; Protein MEL-28; Putative AT-hook-containing transcription factor 1
products gene name :
AHCTF1
other gene names :
AHCTF1; AHCTF1; ELYS; MST108; TMBS62; MSTP108
uniprot entry name :
ELYS_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Probable transcription factor which may play a specific role in hematopoietic tissues. May play a role in early development being critical for the survival of inner cells of the blastocyst (By similarity). [UniProtKB Function]
ncbi acc num :
NP_056261.4
ncbi gb acc num :
NM_015446
ncbi mol weight :
253,460 Da
ncbi pathways :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); Gastric Cancer Network 2 Pathway (760637); M Phase Pathway (105812); Mitotic Anaphase Pathway (105818); Mitotic Metaphase And Anaphase Pathway (730317); Mitotic Prometaphase Pathway (105815); Resolution Of Sister Chromatid Cohesion Pathway (730315); Separation Of Sister Chromatids Pathway (730318)
uniprot summary :
ELYS: Required for the assembly of a functional nuclear pore complex (NPC) on the surface of chromosomes as nuclei form at the end of mitosis. May initiate NPC assembly by binding to chromatin and recruiting the Nup107-160 subcomplex of the NPC. Also required for the localization of the Nup107-160 subcomplex of the NPC to the kinetochore during mitosis and for the completion of cytokinesis. Belongs to the ELYS family. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Transcription factor; DNA-binding. Chromosomal Location of Human Ortholog: 1q44. Cellular Component: nucleoplasm; nuclear membrane; nuclear matrix; nuclear pore; cytosol; chromatin; nucleus. Molecular Function: DNA binding; transcription factor activity. Biological Process: nuclear pore complex assembly; protein transport; mRNA transport; regulation of transcription, DNA-dependent; cytokinesis; mitotic cell cycle