product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human ZW10
catalog :
MBS120277
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3363C4a
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation
more info or order :
product information
catalog number :
MBS120277
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human ZW10
products short name :
ZW10
products name syn :
Homo sapiens ZW10, kinetochore associated, homolog (Drosophila) (ZW10); HZW10; KNTC1AP; MGC149821
other names :
Homo sapiens zw10 kinetochore protein (ZW10), mRNA; Centromere/kinetochore protein zw10 homolog; centromere/kinetochore protein zw10 homolog; ZW10 homolog, centromere/kinetochore protein; ZW10, kinetochore associated, homolog; zeste white 10 homolog; zw10 kinetochore protein
products gene name :
ZW10
other gene names :
ZW10; ZW10; HZW10; KNTC1AP
uniprot entry name :
ZW10_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
3363C4a
host :
Mouse
reactivity :
Human
sequence length :
2964
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The interaction with Sm proteins inhibits their assembly on U RNA and interferes with snRNP biogenesis. Inhibits the binding of survival motor neuron protein (SMN) to Sm proteins. May participate in cellular volume control by activation of a swelling-induced chloride conductance pathway. [UniProtKB Function]
ncbi gi num :
342837718
ncbi acc num :
NP_004715.1
ncbi gb acc num :
NM_004724
ncbi mol weight :
76,807 Da
ncbi pathways :
Cell Cycle Pathway (530733); Cell Cycle, Mitotic Pathway (105765); M Phase Pathway (105812); Mitotic Anaphase Pathway (105818); Mitotic Metaphase And Anaphase Pathway (730317); Mitotic Prometaphase Pathway (105815); Resolution Of Sister Chromatid Cohesion Pathway (730315); Separation Of Sister Chromatids Pathway (730318)
ncbi summary :
This gene encodes a protein that is one of many involved in mechanisms to ensure proper chromosome segregation during cell division. This protein is an essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. [provided by RefSeq, Aug 2011]
uniprot summary :
ZW10: Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Involved in regulation of membrane traffic between the Golgi and the endoplasmic reticulum. Belongs to the ZW10 family. Protein type: Cell cycle regulation. Chromosomal Location of Human Ortholog: 11q23.2. Cellular Component: kinetochore; kinetochore microtubule; spindle pole; endoplasmic reticulum membrane; membrane; endoplasmic reticulum; cytoplasm; nucleus; cytosol. Molecular Function: centromeric DNA binding; protein binding. Biological Process: meiosis; protein transport; ER to Golgi vesicle-mediated transport; establishment of mitotic spindle orientation; mitotic sister chromatid segregation; cell division; mitotic cell cycle checkpoint; regulation of exit from mitosis; protein complex assembly; mitotic cell cycle; Golgi organization and biogenesis; mitotic metaphase plate congression
size1 :
0.1 mg
price1 :
345 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
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