product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human TAX1BP1
catalog :
MBS120264
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3098C2a
reactivity :
human
application :
western blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120264
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human TAX1BP1
products short name :
TAX1BP1
products name syn :
Homo sapiens Tax1 (human T-cell leukemia virus type I) binding protein 1 (TAX1BP1); T6BP; TXBP151; CALCOCO3
other names :
Homo sapiens Tax1 (human T-cell leukemia virus type I) binding protein 1 (TAX1BP1), transcript variant 1, mRNA; Tax1-binding protein 1; tax1-binding protein 1; TRAF6-binding protein; Tax1 (human T-cell leukemia virus type I) binding protein 1; TRAF6-binding protein
products gene name :
TAX1BP1
other gene names :
TAX1BP1; TAX1BP1; T6BP; TXBP151; CALCOCO3
uniprot entry name :
TAXB1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
3098C2a
host :
Mouse
reactivity :
Human
sequence length :
3506
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. [UniProtKB Function]
ncbi gi num :
332634733
ncbi acc num :
NP_006015.4
ncbi gb acc num :
NM_006024
ncbi mol weight :
68,277 Da
ncbi pathways :
Immune System Pathway (106386); Innate Immune System Pathway (106387); Negative Regulators Of RIG-I/MDA5 Signaling Pathway (187102); RIG-I/MDA5 Mediated Induction Of IFN-alpha/beta Pathways (187097)
ncbi summary :
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, May 2011]
uniprot summary :
TAX1BP1: Inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degraded by caspase-3-like family proteins upon TNF-induced apoptosis. May also play a role in the pro-inflammatory cytokine IL-1 signaling cascade. Homooligomer. Interacts with TRAF6 in a IL-1-dependent manner. Interacts with TNFAIP3. Interacts with STARD13. Interacts with the HTLV-1 protein Tax-1. Expressed in all tissues tested. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Apoptosis. Chromosomal Location of Human Ortholog: 7p15. Cellular Component: cytosol. Molecular Function: protein binding; metal ion binding; kinase binding. Biological Process: apoptosis; inhibition of NF-kappaB transcription factor; innate immune response; negative regulation of interferon type I production; negative regulation of apoptosis
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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