product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human TNPO3
catalog :
MBS120261
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
3152C2a
reactivity :
human
application :
western blot, immunocytochemistry
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120261
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human TNPO3
products short name :
TNPO3
products name syn :
Homo sapiens transportin 3 (TNPO3); IPO12; TRNSR; MTR10A;TRN-SR; TRN-SR2
other names :
Homo sapiens transportin 3 (TNPO3), transcript variant 1, mRNA; Transportin-3; transportin-3; imp12; importin 12; limb girdle muscular dystrophy 1F (autosomal dominant); transportin-SR; transportin 3; Importin-12; Imp12; Transportin-SR; TRN-SR
products gene name :
TNPO3
other gene names :
TNPO3; TNPO3; IPO12; TRNSR; LGMD1F; MTR10A; TRN-SR; TRN-SR2
uniprot entry name :
TNPO3_HUMAN
clonality :
Monoclonal
isotype :
IgG2b
clone :
3152C2a
host :
Mouse
reactivity :
Human
sequence length :
4422
form :
Mouse monoclonal anti-human TNPO3 antibody in PBS (3.0 mM KCl, 1.5 mM KH2PO4, 140 mM NaCl, 8.0 mM Na2HPO4(pH7.4)) containing 1% bovine serum albumin (BSA) and 0.05% sodium azide (NaN3).
concentration :
100 ug/ml (1.0 ml)
storage stability :
Store at 2-8 degree C for up to one year. We recommend storing at –20 degree C for long-term storage. Avoid repeat freezing and thawing cycles.
tested application :
Immunocytochemistry (ICC), Western Blot (WB)
app notes :
WB: 0.2-2ug/ml. ICC: 2-100ug/ml
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane. Disposal: This antibody solution contains sodium azide (NaN3) as a preservative. There is a potential hazard that NaN reacts with copper or lead to produce an explosive compound. For safe disposal, the vial has to be washed thoroughly with water.
products description :
TNPO3 is a nuclear import receptor for serine/arginine-rich (SR) proteins, which are essential precursor-mRNA splicing factors (Kataoka et al., 1999).[supplied by OMIM] [NCBI Entrez Gene Summary]
ncbi gi num :
300794233
ncbi acc num :
NP_036602.1
ncbi gb acc num :
NM_012470
ncbi mol weight :
97,372 Da
ncbi summary :
The protein encoded by this gene is a nuclear import receptor for serine/arginine-rich (SR) proteins such as the splicing factors SFRS1 and SFRS2. The encoded protein has also been shown to be involved in HIV-1 infection, apparently through interaction with the HIV-1 capsid protein. Two transcript variants encoding different isoforms as well as a noncoding transcript have been found for this gene.[provided by RefSeq, Jul 2010]
uniprot summary :
IPO3: Seems to function in nuclear protein import as nuclear transport receptor. In vitro, mediates the nuclear import of splicing factor SR proteins RBM4, SFRS1 and SFRS2, by recognizing phosphorylated RS domains. 3 isoforms of the human protein are produced by alternative splicing. Protein type: Nuclear export; Karyopherin; Receptor, misc.; Nuclear import. Chromosomal Location of Human Ortholog: 7q32.1. Cellular Component: intracellular membrane-bound organelle; cytoplasm; nucleus. Molecular Function: protein binding; receptor activity. Biological Process: splicing factor protein import into nucleus. Disease: Muscular Dystrophy, Limb-girdle, Type 1f
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!