Mouse monoclonal antibody Anti-Human FER | MyBioSource MBS120259 product information

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse monoclonal antibody Anti-Human FER

catalog :

MBS120259

quantity :

0.1 mg

price :

345 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2358C3a

reactivity :

human

application :

western blot, immunoprecipitation

more info or order :

MyBioSource product webpage

product information

catalog number :

MBS120259

products type :

Antibody

products full name :

Mouse monoclonal antibody Anti-Human FER

products short name :

FER

products name syn :

Homo sapiens fer (fps/fes related) tyrosine kinase (phosphoprotein NCP94) (FER); TYK3

other names :

Homo sapiens fer (fps/fes related) tyrosine kinase (FER), mRNA; Tyrosine-protein kinase Fer; tyrosine-protein kinase Fer; feline encephalitis virus-related kinase FER; fujinami poultry sarcoma/Feline sarcoma-related protein Fer; p94-Fer; phosphoprotein NCP94; protein phosphatase 1, regulatory subunit 74; proto-oncogene c-Fer; truncated fer (fps/fes related) tyrosine kinase; tyrosine kinase 3; fer (fps/fes related) tyrosine kinase; Feline encephalitis virus-related kinase FER; Fujinami poultry sarcoma/Feline sarcoma-related protein Fer; Proto-oncogene c-Fer; Tyrosine kinase 3; p94-Fer

products gene name :

FER

other gene names :

FER; FER; FerT; TYK3; Pe1Fe3; Pe1Fe6; PPP1R74; Pe1Fe10; Pe1Fe13

uniprot entry name :

FER_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

2358C3a

host :

Mouse

reactivity :

Human

sequence length :

2950

concentration :

100 ug/ml (1.0 ml)

tested application :

Dot Blot (DB), Immunoprecipitation (IP), Western Blot (WB)

other info1 :

Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.

other info2 :

Sterility: Filtered through a 0.22 um membrane.

products description :

Fer protein is a member of the FPS/FES family of nontransmembrane receptor tyrosine kinases. It regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. [NCBI Entrez Gene Summary]

ncbi gi num :

119964720

ncbi acc num :

NP_005237.2

ncbi gb acc num :

NM_005246

ncbi mol weight :

51,643 Da

ncbi pathways :

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Fc-epsilon Receptor I Signaling In Mast Cells Pathway (138050); Integrated Breast Cancer Pathway (219801); N-cadherin Signaling Events Pathway (137919); PDGFR-beta Signaling Pathway (138071); Signal Transduction Pathway (477114); Signaling By SCF-KIT Pathway (477120); Signaling Events Mediated By PTP1B Pathway (138017); Signaling Events Mediated By Stem Cell Factor Receptor (c-Kit) Pathway (138068)

ncbi summary :

uniprot summary :

Fer: a non-receptor tyrosine kinase of the Fer family. Regulates cell-cell adhesion and mediates signaling from the cell surface to the cytoskeleton via growth factor receptors. Increased expression associated with prostate cancer proliferation, and antisense blocks soft agar growth. Protein type: Kinase, protein; EC 2.7.10.2; Protein kinase, TK; Protein kinase, tyrosine (non-receptor); Oncoprotein; TK group; Fer family. Chromosomal Location of Human Ortholog: 5q21. Cellular Component: microtubule cytoskeleton; extrinsic to internal side of plasma membrane; lamellipodium; cytoplasm; nuclear chromatin; cell cortex; cytosol; nucleus; cell junction; actin cytoskeleton. Molecular Function: protein binding; cadherin binding; protein-tyrosine kinase activity; gamma-catenin binding; non-membrane spanning protein tyrosine kinase activity; actin binding; protein kinase binding; lipid binding; protein phosphatase 1 binding; Rab GTPase binding; ATP binding; epidermal growth factor receptor binding. Biological Process: regulation of mast cell degranulation; peptidyl-tyrosine phosphorylation; diapedesis; protein amino acid autophosphorylation; tyrosine phosphorylation of Stat3 protein; negative regulation of mast cell activation during immune response; platelet-derived growth factor receptor signaling pathway; response to lipopolysaccharide; chemotaxis; protein amino acid phosphorylation; activation of NF-kappaB transcription factor; positive regulation of cell proliferation; cell adhesion; cell differentiation; regulation of protein amino acid phosphorylation; cytokine and chemokine mediated signaling pathway; microtubule cytoskeleton organization and biogenesis; regulation of epidermal growth factor receptor signaling pathway; regulation of cell proliferation; cell proliferation; cellular response to insulin stimulus; positive regulation of actin filament polymerization; actin cytoskeleton reorganization; innate immune response; mitotic cell cycle; positive regulation of cell migration

size1 :

0.1 mg

price1 :

345 USD

more info or order :

MyBioSource product webpage