product summary
Loading...
company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human NUDT21
catalog :
MBS120191
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2203C3
reactivity :
human
application :
western blot, immunocytochemistry, immunoprecipitation, flow cytometry, FACS
more info or order :
product information
catalog number :
MBS120191
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human NUDT21
products short name :
NUDT21
products name syn :
Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 21 (NUDT21), mRNA; CPSF5; CFIM25; DKFZp686H1588
other names :
Homo sapiens nudix (nucleoside diphosphate linked moiety X)-type motif 21 (NUDT21), mRNA; Cleavage and polyadenylation specificity factor subunit 5; cleavage and polyadenylation specificity factor subunit 5; CPSF 25 kDa subunit; cleavage and polyadenylation specific factor 5, 25 kD subunit; cleavage and polyadenylation specific factor 5, 25 kDa; cleavage and polyadenylation specificity factor 25 kDa subunit; cleavage factor Im complex 25 kDa subunit; nucleoside diphosphate-linked moiety X motif 21; nudix motif 21; pre-mRNA cleavage factor Im (25kD); pre-mRNA cleavage factor Im 25 kDa subunit; pre-mRNA cleavage factor Im, 25kD subunit; nudix (nucleoside diphosphate linked moiety X)-type motif 21; Cleavage and polyadenylation specificity factor 25 kDa subunit; CFIm25; CPSF 25 kDa subunit; Nucleoside diphosphate-linked moiety X motif 21; Nudix motif 21; Pre-mRNA cleavage factor Im 25 kDa subunit
products gene name :
NUDT21
other gene names :
NUDT21; NUDT21; CPSF5; CFIM25
uniprot entry name :
CPSF5_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2203C3
host :
Mouse
reactivity :
Human
sequence length :
4407
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [NCBI Entrez Gene Summary]
ncbi gi num :
59889569
ncbi acc num :
NP_008937.1
ncbi gb acc num :
NM_007006
ncbi mol weight :
26,227 Da
ncbi pathways :
Cleavage Of Growing Transcript In The Termination Region Pathway (106560); Gene Expression Pathway (105937); Processing Of Capped Intron-Containing Pre-mRNA Pathway (160950); Processing Of Capped Intronless Pre-mRNA Pathway (160951); Processing Of Intronless Pre-mRNAs Pathway (160954); RNA Polymerase II Transcription Pathway (106557); RNA Polymerase II Transcription Termination Pathway (106559); MRNA 3'-end Processing Pathway (105957); MRNA Splicing Pathway (105951); MRNA Splicing - Major Pathway (105952)
ncbi summary :
The protein encoded by this gene is one subunit of a cleavage factor required for 3' RNA cleavage and polyadenylation processing. The interaction of the protein with the RNA is one of the earliest steps in the assembly of the 3' end processing complex and facilitates the recruitment of other processing factors. This gene encodes the 25kD subunit of the protein complex, which is composed of four polypeptides. [provided by RefSeq, Jul 2008]
uniprot summary :
CFIM25: Component of the cleavage factor Im (CFIm) complex that plays a key role in pre-mRNA 3 -processing. Involved in association with CPSF6 or CPSF7 in pre-MRNA 3 -end poly(A) site cleavage and poly(A) addition. NUDT21/CPSF5 binds to cleavage and polyadenylation RNA substrates. The homodimer mediates simultaneous sequence-specific recognition of two 5 -UGUA-3 elements within the pre-mRNA. Binds to, but does not hydrolyze mono- and di-adenosine nucleotides. May have a role in mRNA export. Belongs to the Nudix hydrolase family. CPSF5 subfamily. Protein type: RNA splicing; Spliceosome; RNA-binding. Chromosomal Location of Human Ortholog: 16q12.2. Cellular Component: nucleoplasm; centrosome; paraspeckles; nucleus; mRNA cleavage factor complex. Molecular Function: mRNA binding; protein binding; protein homodimerization activity; hydrolase activity; RNA binding; histone deacetylase binding; AU-rich element binding. Biological Process: transcription from RNA polymerase II promoter; nuclear mRNA splicing, via spliceosome; RNA splicing; gene expression; mRNA polyadenylation; mRNA 3 -end processing; mRNA processing; termination of RNA polymerase II transcription; protein tetramerization
size1 :
0.1 mg
price1 :
345 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."
Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...
"MyBioSource offers the best products at unbeatable prices."
Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.
Would you like to receive email and e-newsletter from MyBioSource about new products, special offers and events? Please click here to join our Mailing List!
browse more products
questions and comments