catalog number :
MBS120168
products full name :
Mouse monoclonal antibody Anti-Human DDX39
products short name :
DDX39
products name syn :
Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 39 (DDX39), transcript variant 2; BAT1; DDXL; URH49; MGC8417; MGC18203
other names :
ATP-dependent RNA helicase DDX39A; ATP-dependent RNA helicase DDX39A; DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A; DEAD box protein 39; Nuclear RNA helicase URH49
products gene name :
DDX39
other gene names :
DDX39A; DDX39A; BAT1; DDXL; BAT1L; DDX39; URH49
uniprot entry name :
DX39A_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. [NCBI Entrez Gene Summary]
ncbi acc num :
NP_620551.1
ncbi gb acc num :
NM_138998
ncbi mol weight :
30,488 Da
ncbi summary :
This gene encodes a member of the DEAD box protein family. These proteins are characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD) and are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure, such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of the DEAD box protein family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene is thought to play a role in the prognosis of patients with gastrointestinal stromal tumors. A pseudogene of this gene is present on chromosome 13. Alternate splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Sep 2013]
uniprot summary :
DDX39: Involved in pre-mRNA splicing. Required for the export of mRNA out of the nucleus. Belongs to the DEAD box helicase family. DECD subfamily. Protein type: EC 3.6.4.13; Helicase; RNA-binding; RNA splicing. Chromosomal Location of Human Ortholog: 19p13.12. Cellular Component: membrane; cytoplasm; nucleus. Molecular Function: protein binding; helicase activity; ATP binding. Biological Process: nuclear mRNA splicing, via spliceosome; mRNA export from nucleus