Mouse monoclonal antibody Anti-Human CTNND1 | MyBioSource MBS120161 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

MyBioSource

product type :

antibody

product name :

Mouse monoclonal antibody Anti-Human CTNND1

catalog :

MBS120161

quantity :

0.1 mg

price :

345 USD

clonality :

monoclonal

host :

mouse

conjugate :

nonconjugated

clone name :

2234C6a

reactivity :

human

application :

western blot, immunocytochemistry, immunoprecipitation, flow cytometry, FACS

product information

catalog number :

MBS120161

products type :

Antibody

products full name :

Mouse monoclonal antibody Anti-Human CTNND1

products short name :

CTNND1

products name syn :

Homo sapiens catenin (cadherin-associated protein), delta 1 (CTNND1); CAS; p120; CTNND; P120CAS; P120CTN; KIAA0384

other names :

Homo sapiens catenin (cadherin-associated protein), delta 1 (CTNND1), transcript variant 3, mRNA; Catenin delta-1; catenin delta-1; cadherin-associated Src substrate; p120 catenin; catenin (cadherin-associated protein), delta 1; Cadherin-associated Src substrate; CAS; p120 catenin; p120(ctn); p120(cas)

products gene name :

CTNND1

other gene names :

CTNND1; CTNND1; CAS; p120; CTNND; P120CAS; P120CTN; p120(CAS); p120(CTN)

uniprot entry name :

CTND1_HUMAN

clonality :

Monoclonal

isotype :

IgG1

clone :

2234C6a

host :

Mouse

reactivity :

Human

sequence length :

6282

concentration :

100 ug/ml (1.0 ml)

tested application :

Dot Blot (DB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)

other info1 :

Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.

other info2 :

Sterility: Filtered through a 0.22 um membrane.

products description :

This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and althernative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. [NCBI Entrez Gene Summary]

ncbi gi num :

146231983

ncbi acc num :

NP_001322.1

ncbi gb acc num :

NM_001331

ncbi mol weight :

65,641 Da

ncbi pathways :

Adherens Junction Pathway (83070); Adherens Junction Pathway (481); Adherens Junctions Interactions Pathway (119533); Arf6 Trafficking Events Pathway (137954); Cell Junction Organization Pathway (160966); Cell-Cell Communication Pathway (477132); Cell-cell Junction Organization Pathway (119532); E-cadherin Signaling In Keratinocytes Pathway (138002); E-cadherin Signaling In The Nascent Adherens Junction Pathway (138005); EGFR1 Signaling Pathway (198782)

ncbi summary :

This gene encodes a member of the Armadillo protein family, which function in adhesion between cells and signal transduction. Multiple translation initiation codons and alternative splicing result in many different isoforms being translated. Not all of the full-length natures of the described transcript variants have been determined. Read-through transcription also exists between this gene and the neighboring upstream thioredoxin-related transmembrane protein 2 (TMX2) gene. [provided by RefSeq, Dec 2010]

uniprot summary :

CTNND1: an Arm repeat protein that interacts with varied components such as cadherin, small G proteins, kinases, and the Kaiso transcriptional repressor. A downstream modulator of Wnt/beta-catenin signaling pathway whose stability may be regulated downstream of Dsh. Required for the invasiveness of E-cadherin-deficient cells. A signal coordinator between cadherins and Rho-family GTPases to regulate cytoskeletal changes required during dendritic spine and synapse development. The association of catenins with cadherins produces a complex which is linked to the actin filament network, and which seems to be of primary importance for cadherins cell-adhesion properties. Thirty two splice-variant isoforms have been described. Protein type: Adaptor/scaffold; Actin-binding; G protein regulator, misc.; Motility/polarity/chemotaxis; Cell adhesion. Chromosomal Location of Human Ortholog: 11q11. Cellular Component: growth cone; lamellipodium; cytoplasm; plasma membrane; dendritic spine; synapse; intercellular junction; midbody; zonula adherens; nucleus; cytosol. Molecular Function: protein binding; cadherin binding; protein kinase binding; receptor binding. Biological Process: intercellular junction assembly and maintenance; cell-cell adhesion; Wnt receptor signaling pathway; transcription, DNA-dependent; regulation of transcription, DNA-dependent; brain development; vascular endothelial growth factor receptor signaling pathway; cell adhesion

size1 :

0.1 mg

price1 :

345 USD