product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human BCL9
catalog :
MBS120150
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2071C3a
reactivity :
human
application :
western blot, dot blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120150
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human BCL9
products short name :
BCL9
products name syn :
Homo sapiens B-cell CLL/lymphoma 9 (BCL9); LGS; MGC131591
other names :
Homo sapiens B-cell CLL/lymphoma 9 (BCL9), mRNA; B-cell CLL/lymphoma 9 protein; B-cell CLL/lymphoma 9 protein; B-cell lymphoma 9 protein; bcl-9; protein legless homolog; B-cell CLL/lymphoma 9; Protein legless homolog
products gene name :
BCL9
other gene names :
BCL9; BCL9; LGS
uniprot entry name :
BCL9_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2071C3a
host :
Mouse
reactivity :
Human
sequence length :
6192
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [NCBI Entrez Gene Summary]
ncbi gi num :
523425752
ncbi acc num :
NP_004317.2
ncbi gb acc num :
NM_004326
ncbi mol weight :
149,290 Da
ncbi pathways :
Disease Pathway (530764); RNF Mutants Show Enhanced WNT Signaling And Proliferation Pathway (1127632); Regulation Of Wnt-mediated Beta Catenin Signaling And Target Gene Transcription Pathway (169352); Signal Transduction Pathway (477114); Signaling By WNT In Cancer Pathway (1127614); Signaling By Wnt Pathway (106510); TCF Dependent Signaling In Response To WNT Pathway (1127516); Wnt Signaling Pathway NetPath (198799); XAV939 Inhibits Tankyrase, Stabilizing AXIN Pathway (1127633); Deactivation Of The Beta-catenin Transactivating Complex Pathway (1127521)
ncbi summary :
BCL9 is associated with B-cell acute lymphoblastic leukemia. It may be a target of translocation in B-cell malignancies with abnormalities of 1q21. Its function is unknown. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies. [provided by RefSeq, Jul 2008]
uniprot summary :
Bcl-9: Involved in signal transduction through the Wnt pathway. Promotes beta-catenin s transcriptional activity. A chromosomal aberration involving BCL9 is found in a patient with precusor B-cell acute lymphoblastic leukemia (ALL). Translocation t(1;14)(q21;q32). This translocation leaves the coding region intact, but may have pathogenic effects due to alterations in the expression level of BCL9. Several cases of translocations within the 3 -UTR of BCL9 have been found in B-cell malignancies. Belongs to the BCL9 family. Protein type: Transcription factor; Oncoprotein. Chromosomal Location of Human Ortholog: 1q21. Cellular Component: nucleoplasm; Golgi apparatus; cis-Golgi network. Molecular Function: protein binding; beta-catenin binding. Biological Process: regulation of transforming growth factor beta receptor signaling pathway; somatic stem cell maintenance; myotube differentiation involved in skeletal muscle regeneration; positive regulation of transcription from RNA polymerase II promoter; Wnt receptor signaling pathway through beta-catenin
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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