product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human CHTF18
catalog :
MBS120149
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2182C3a
reactivity :
human
application :
western blot, immunoprecipitation
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120149
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human CHTF18
products short name :
CHTF18
products name syn :
Homo sapiens CTF18, chromosome transmission fidelity factor 18?homolog (S. cerevisiae) (CHTF18); CHL12; Ctf18; RUVBL;C16orf41; C321D2.2; C321D2.3; C321D2.4
other names :
Homo sapiens CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae) (CHTF18), mRNA; Chromosome transmission fidelity protein 18 homolog; chromosome transmission fidelity protein 18 homolog; C321D2.3 (novel protein); C321D2.4 (novel protein); hCTF18; homolog of yeast CHL12; some homology with holliday junction DNA helicase RUVB like; CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae); CHL12
products gene name :
CHTF18
other gene names :
CHTF18; CHTF18; CHL12; Ctf18; RUVBL; C16orf41; C321D2.2; C321D2.3; C321D2.4
uniprot entry name :
CTF18_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2182C3a
host :
Mouse
reactivity :
Human
sequence length :
3096
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunoprecipitation (IP), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
ncbi gi num :
157951660
ncbi acc num :
NP_071375.1
ncbi gb acc num :
NM_022092
ncbi mol weight :
61,869 Da
ncbi pathways :
Gastric Cancer Network 2 Pathway (760637)
ncbi summary :
CHTF18, CHTF8 (MIM 613202), and DCC1 (DSCC1; MIM 613203) are components of an alternative replication factor C (RFC) (see MIM 600404) complex that loads PCNA (MIM 176740) onto DNA during S phase of the cell cycle (Merkle et al., 2003 [PubMed 12766176]; Bermudez et al., 2003 [PubMed 12930902]).[supplied by OMIM, Dec 2009]
uniprot summary :
CTF18: Chromosome cohesion factor involved in sister chromatid cohesion and fidelity of chromosome transmission. Component of one of the cell nuclear antigen loader complexes, CTF18-replication factor C (CTF18-RFC), which consists of CTF18, CTF8, DCC1, RFC2, RFC3, RFC4 and RFC5. The CTF18-RFC complex binds to single- stranded and primed DNAs and has weak ATPase activity that is stimulated by the presence of primed DNA, replication protein A (RPA) and by proliferating cell nuclear antigen (PCNA). The CTF18- RFC complex catalyzes the ATP-dependent loading of PCNA onto primed and gapped DNA. It also interacts with and stimulates DNA polymerase POLH. Belongs to the activator 1 small subunits family. CTF18 subfamily. 3 isoforms of the human protein are produced by alternative splicing. Protein type: DNA replication. Chromosomal Location of Human Ortholog: 16p13.3. Cellular Component: nucleoplasm; membrane; cytoplasm. Molecular Function: DNA binding; ATP binding. Biological Process: negative regulation of chromosome segregation; meiotic recombination; spermatogenesis; DNA replication; male meiosis
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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