catalog number :
MBS120148
products full name :
Mouse monoclonal antibody Anti-Human CHD6
products short name :
CHD6
products name syn :
Homo sapiens chromodomain helicase DNA binding protein 6 (CHD6); CHD5; RIGB; KIAA1335
other names :
Homo sapiens chromodomain helicase DNA binding protein 6 (CHD6), mRNA; Chromodomain-helicase-DNA-binding protein 6; chromodomain-helicase-DNA-binding protein 6; ATP-dependent helicase CHD6; helicase C-terminal domain- and SNF2 N-terminal domain-containing protein; radiation-induced gene B protein; chromodomain helicase DNA binding protein 6; ATP-dependent helicase CHD6; Radiation-induced gene B protein
products gene name :
CHD6
other gene names :
CHD6; CHD6; CHD5; RIGB; CHD-6
uniprot entry name :
CHD6_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Chromosomal DNA of eukaryotic cells is compacted by nuclear proteins to form chromatin, an organized nucleoprotein structure that can inhibit gene expression. Several multisubunit protein complexes exist to remodel the chromatin to allow patterns of cell type-specific gene expression. The protein encoded by this gene is thought to be a core member of one or more of these complexes. The encoded protein, which is a member of the SNF2/RAD54 helicase family, contains two chromodomains, a helicase domain, and an ATPase domain. [NCBI Entrez Gene Summary]
ncbi acc num :
NP_115597.3
ncbi gb acc num :
NM_032221
ncbi mol weight :
94,609 Da
ncbi summary :
This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specific gene expression, and the encoded protein is thought to be a core member of one or more of these chromatin remodeling complexes. The encoded protein may function as a transcriptional repressor and is involved in the cellular repression of influenza virus replication. [provided by RefSeq, Jul 2013]