catalog number :
MBS120141
products full name :
Mouse monoclonal antibody Anti-Human CDC5L
products short name :
CDC5L
products name syn :
Homo sapiens CDC5 cell division cycle 5-like (S. pombe) (CDC5L); CEF1; hCDC5; PCDC5RP; KIAA0432; dJ319D22.1
other names :
Homo sapiens cell division cycle 5-like (CDC5L), mRNA; Cell division cycle 5-like protein; cell division cycle 5-like protein; CDC5 cell division cycle 5-like; Cdc5-related protein; dJ319D22.1 (CDC5-like protein); pombe cdc5-related protein; cell division cycle 5-like; Pombe cdc5-related protein
products gene name :
CDC5L
other gene names :
CDC5L; CDC5L; CDC5; CEF1; PCDC5RP; CDC5-LIKE; dJ319D22.1
uniprot entry name :
CDC5L_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. [NCBI Entrez Gene Summary]
ncbi acc num :
NP_001244.1
ncbi gb acc num :
NM_001253
ncbi mol weight :
92,251 Da
ncbi pathways :
Gene Expression Pathway 105937!!Processing Of Capped Intron-Containing Pre-mRNA Pathway 160950!!Spliceosome Pathway 125136!!Spliceosome Pathway 124832!!Spliceosome, 35S U5-snRNP Pathway 413438!!Spliceosome, 35S U5-snRNP Pathway 890602!!Spliceosome, Prp19/CDC5L Complex Pathway 413437!!Spliceosome, Prp19/CDC5L Complex Pathway 890600!!MRNA Splicing Pathway 105951!!MRNA Splicing - Major Pathway 105952
ncbi summary :
The protein encoded by this gene shares a significant similarity with Schizosaccharomyces pombe cdc5 gene product, which is a cell cycle regulator important for G2/M transition. This protein has been demonstrated to act as a positive regulator of cell cycle G2/M progression. It was also found to be an essential component of a non-snRNA spliceosome, which contains at least five additional protein factors and is required for the second catalytic step of pre-mRNA splicing. [provided by RefSeq, Jul 2008]