product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human MYCN
catalog :
MBS120139
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
986C1a
reactivity :
human
application :
western blot, dot blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120139
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human MYCN
products short name :
MYCN
products name syn :
Homo sapiens v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian); ODED; MODED; N-myc
other names :
Homo sapiens v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian), mRNA; N-myc proto-oncogene protein; N-myc proto-oncogene protein; class E basic helix-loop-helix protein 37; neuroblastoma MYC oncogene; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene; oncogene NMYC; pp65/67; v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog; Class E basic helix-loop-helix protein 37; bHLHe37
products gene name :
MYCN
other gene names :
MYCN; MYCN; NMYC; ODED; MODED; N-myc; bHLHe37
uniprot entry name :
MYCN_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
986C1a
host :
Mouse
reactivity :
Human
sequence length :
2458
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. [NCBI Entrez Gene Summary]
ncbi gi num :
33877057
ncbi acc num :
BC002712
ncbi mol weight :
49,561 Da
ncbi pathways :
Transcriptional Misregulation In Cancer Pathway (523016); Transcriptional Misregulation In Cancer Pathway (522987)
ncbi summary :
This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]
uniprot summary :
N-Myc: a proto-oncogenic transcription factor. Plays a role in cell proliferation, apoptosis and in the development of human tumors. Protein type: Oncoprotein; DNA-binding; Transcription factor. Chromosomal Location of Human Ortholog: 2p24.3. Cellular Component: chromatin; nucleus. Molecular Function: protein dimerization activity; protein binding; DNA binding; transcription factor activity. Biological Process: regulation of transcription from RNA polymerase II promoter; branching morphogenesis of a tube; negative regulation of astrocyte differentiation; positive regulation of mesenchymal cell proliferation; positive regulation of transcription from RNA polymerase II promoter; embryonic digit morphogenesis; embryonic skeletal morphogenesis; lung development; cartilage condensation. Disease: Feingold Syndrome 1; Tracheoesophageal Fistula With Or Without Esophageal Atresia
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

"MyBioSource offers the best products at unbeatable prices."

Please spend a few minutes to browse our online catalogs and see the wide range of products available. We ship our products through our shipping/distribution facility in San Diego, California, USA.

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