catalog number :
MBS120121
products full name :
Mouse monoclonal antibody Anti-Human TARS
products short name :
TARS
products name syn :
Homo sapiens threonyl-tRNA synthetase, mRNA (cDNA clone MGC:9344 IMAGE:3458845), complete cds; ThrRS; MGC9344
other names :
Homo sapiens threonyl-tRNA synthetase, mRNA; Threonine--tRNA ligase, cytoplasmic; threonine--tRNA ligase, cytoplasmic; threonine tRNA ligase 1, cytoplasmic; threonyl-tRNA synthetase, cytoplasmic; threonyl-tRNA synthetase; Threonyl-tRNA synthetase; ThrRS
products gene name :
TARS
other gene names :
TARS; TARS; ThrRS
uniprot entry name :
SYTC_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [NCBI Entrez Gene Summary]
ncbi mol weight :
86,861 Da
ncbi pathways :
Aminoacyl-tRNA Biosynthesis Pathway (83030); Aminoacyl-tRNA Biosynthesis Pathway (424); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (413439); Aminoacyl-tRNA Biosynthesis, Eukaryotes Pathway (468360); Cytosolic TRNA Aminoacylation Pathway (105981); Gene Expression Pathway (105937); TRNA Aminoacylation Pathway (105980)
ncbi summary :
Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [provided by RefSeq, Jul 2008]
uniprot summary :
TARS: Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II aminoacyl-tRNA synthetase family [provided by RefSeq, Jul 2008]. Protein type: EC 6.1.1.3; Translation; Ligase. Chromosomal Location of Human Ortholog: 5p13.2. Cellular Component: cytoplasm; cytosol; actin cytoskeleton. Molecular Function: threonine-tRNA ligase activity; protein homodimerization activity; ATP binding. Biological Process: tRNA aminoacylation for protein translation; translation; threonyl-tRNA aminoacylation; gene expression