product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human BTG1
catalog :
MBS120115
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2095C1a
reactivity :
human
application :
western blot, dot blot
more info or order :
MyBioSource product webpage
product information
catalog number :
MBS120115
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human BTG1
products short name :
BTG1
products name syn :
Homo sapiens B-cell translocation gene 1, anti-proliferative (BTG1), mRNA
other names :
Homo sapiens B-cell translocation gene 1, anti-proliferative (BTG1), mRNA; protein BTG1; B-cell translocation gene 1 protein; B-cell translocation gene 1, anti-proliferative
products gene name :
BTG1
other gene names :
BTG1; BTG1
uniprot entry name :
BTG1_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2095C1a
host :
Mouse
reactivity :
Human
sequence length :
4704
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The BTG1 gene locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. It is a member of a family of antiproliferative genes. BTG1 expression is maximal in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. It negatively regulates cell proliferation. [NCBI Entrez Gene Summary]
ncbi gi num :
209447059
ncbi acc num :
NP_001722.1
ncbi gb acc num :
NM_001731
ncbi mol weight :
19,209 Da
ncbi pathways :
Diurnally Regulated Genes With Circadian Orthologs Pathway (198813); RNA Degradation Pathway (117291); RNA Degradation Pathway (116127)
ncbi summary :
This gene is a member of an anti-proliferative gene family that regulates cell growth and differentiation. Expression of this gene is highest in the G0/G1 phases of the cell cycle and downregulated when cells progressed through G1. The encoded protein interacts with several nuclear receptors, and functions as a coactivator of cell differentiation. This locus has been shown to be involved in a t(8;12)(q24;q22) chromosomal translocation in a case of B-cell chronic lymphocytic leukemia. [provided by RefSeq, Oct 2008]
uniprot summary :
BTG1: Anti-proliferative protein. A chromosomal aberration involving BTG1 may be a cause of a form of B-cell chronic lymphocytic leukemia. Translocation t(8;12)(q24;q22) with MYC. Belongs to the BTG family. Protein type: Oncoprotein; Cell cycle regulation. Chromosomal Location of Human Ortholog: 12q22. Cellular Component: cytoplasm; nucleus. Molecular Function: protein binding; enzyme binding; transcription cofactor activity; kinase binding. Biological Process: negative regulation of cell proliferation; positive regulation of angiogenesis; cell migration; positive regulation of endothelial cell differentiation; regulation of transcription, DNA-dependent; negative regulation of cell growth; positive regulation of myoblast differentiation
size1 :
0.1 mg
price1 :
345 USD
more info or order :
MyBioSource product webpage
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

"MyBioSource's number 1 vision is to be the world's number 1 quality reagents provider."

Our goal is to provide researchers, scientists and customers alike with a one-stop-shop for all of their reagents needs, whether it is monoclonal antibody, polyclonal antibody, recombinant protein, peptide, etc...

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