catalog number :
MBS120114
products full name :
Mouse monoclonal antibody Anti-Human BRPF1
products short name :
BRPF1
products name syn :
Homo sapiens bromodomain and PHD finger containing, 1 (BRPF1), transcript variant 1, mRNA; BR140
other names :
Homo sapiens bromodomain and PHD finger containing, 1 (BRPF1), transcript variant 1, mRNA; Peregrin; peregrin; bromodomain and PHD finger-containing protein 1; bromodomain-containing protein, 140kD; bromodomain and PHD finger containing, 1; Bromodomain and PHD finger-containing protein 1; Protein Br140
products gene name :
BRPF1
other gene names :
BRPF1; BRPF1; BR140
uniprot entry name :
BRPF1_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunoprecipitation (IP), Western Blot (WB), Flow Cytometry (FC/FACS)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
The protein encoded by this gene is expressed ubiquitously and at the highest level in testes and spermatogonia. The protein is localized within nuclei, and it is very similar in structure to two zinc finger proteins, AF10 and AF17. It is suggested that these proteins form a family of regulatory proteins. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [NCBI Entrez Gene Summary]
ncbi acc num :
NP_001003694.1
ncbi gb acc num :
NM_001003694
ncbi mol weight :
127,363 Da
ncbi pathways :
Chromatin Modifying Enzymes Pathway (1127682); Chromatin Organization Pathway (1127681); HATs Acetylate Histones Pathway (1127683)
ncbi summary :
The protein encoded by this gene is expressed ubiquitously and at the highest level in testes and spermatogonia. The protein is localized within nuclei, and it is very similar in structure to two zinc finger proteins, AF10 and AF17. It is suggested that these proteins form a family of regulatory proteins. Two alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
uniprot summary :
peregrin: Component of the MOZ/MORF complex which has a histone H3 acetyltransferase activity. Positively regulates the transcription of RUNX1 and RUNX2. 4 isoforms of the human protein are produced by alternative splicing. Protein type: C2H2-type zinc finger protein. Chromosomal Location of Human Ortholog: 3p26-p25. Cellular Component: nucleoplasm; cytoplasm; nucleus. Molecular Function: protein binding; DNA binding; zinc ion binding. Biological Process: establishment and/or maintenance of chromatin architecture; transcription, DNA-dependent; positive regulation of transcription, DNA-dependent