product summary
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company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human ANKRD11
catalog :
MBS120106
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2022C8a
reactivity :
human
application :
western blot
more info or order :
product information
catalog number :
MBS120106
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human ANKRD11
products short name :
ANKRD11
products name syn :
Homo sapiens ankyrin repeat domain 11 (ANKRD11), mRNA; T13; LZ16; ANCO-1
other names :
Homo sapiens ankyrin repeat domain 11 (ANKRD11), transcript variant 2, mRNA; Ankyrin repeat domain-containing protein 11; ankyrin repeat domain-containing protein 11; ankyrin repeat-containing cofactor 1; nasopharyngeal carcinoma susceptibility protein; ankyrin repeat domain 11; Ankyrin repeat-containing cofactor 1
products gene name :
ANKRD11
other gene names :
ANKRD11; ANKRD11; T13; LZ16; ANCO1; ANCO-1
uniprot entry name :
ANR11_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2022C8a
host :
Mouse
reactivity :
Human
sequence length :
9310
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Western Blot (WB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. [UniProtKB Function]
ncbi gi num :
371874333
ncbi acc num :
NP_037407.4
ncbi gb acc num :
NM_013275
ncbi mol weight :
297,913 Da
ncbi summary :
This locus encodes an ankryin repeat domain-containing protein. The encoded protein inhibits ligand-dependent activation of transcription. Mutations in this gene have been associated with KBG syndrome, which is characterized by macrodontia, distinctive craniofacial features, short stature, skeletal anomalies, global developmental delay, seizures and intellectual disability. Alternatively spliced transcript variants have been described. Related pseudogenes exist on chromosomes 2 and X. [provided by RefSeq, Jan 2012]
uniprot summary :
ANKRD11: May recruit HDACs to the p160 coactivators/nuclear receptor complex to inhibit ligand-dependent transactivation. Defects in ANKRD11 are the cause of KBG syndrome (KBGS). A syndrome characterized by macrodontia of the upper central incisors, distinctive craniofacial findings, short stature, skeletal anomalies, and neurologic involvement that includes global developmental delay, seizures, and intellectual disability. Protein type: Nuclear receptor co-regulator; Transcription, coactivator/corepressor. Chromosomal Location of Human Ortholog: 16q24.3. Cellular Component: nucleoplasm; cytoplasm; plasma membrane; nucleus. Biological Process: in utero embryonic development; skeletal morphogenesis; multicellular organism growth; tissue homeostasis; odontogenesis of dentine-containing teeth. Disease: Kbg Syndrome
size1 :
0.1 mg
price1 :
345 USD
more info or order :
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.
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