catalog number :
MBS120105
products full name :
Mouse monoclonal antibody Anti-Human USF2
products short name :
USF2
products name syn :
H.sapiens USF2 gene
other names :
H.sapiens USF2 gene; Upstream stimulatory factor 2; Class B basic helix-loop-helix protein 12; bHLHb12; FOS-interacting protein; FIP; Major late transcription factor 2; Upstream transcription factor 2
products gene name :
USF2
uniprot entry name :
USF2_HUMAN
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB), Immunocytochemistry (ICC)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene. [NCBI Entrez Gene Summary]
ncbi acc num :
CAA68942.1
ncbi mol weight :
23,988 Da
uniprot summary :
USF2: Transcription factor that binds to a symmetrical DNA sequence (E-boxes) (5 -CACGTG-3 ) that is found in a variety of viral and cellular promoters. 3 isoforms of the human protein are produced by alternative splicing. Protein type: DNA-binding. Chromosomal Location of Human Ortholog: 19q13. Cellular Component: nucleoplasm; nucleus. Molecular Function: RNA polymerase II transcription factor activity, enhancer binding; protein binding; protein homodimerization activity; protein heterodimerization activity; sequence-specific DNA binding; double-stranded DNA binding; bHLH transcription factor binding; transcription factor activity. Biological Process: lactation; transcription from RNA polymerase II promoter; regulation of transcription from RNA polymerase II promoter by glucose; lipid homeostasis; late viral mRNA transcription; positive regulation of transcription from RNA polymerase II promoter by glucose; positive regulation of transcription from RNA polymerase II promoter