This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
MyBioSource
product type :
antibody
product name :
Mouse monoclonal antibody Anti-Human DBF4
catalog :
MBS120101
quantity :
0.1 mg
price :
345 USD
clonality :
monoclonal
host :
mouse
conjugate :
nonconjugated
clone name :
2047C4a
reactivity :
human
application :
western blot, dot blot
citations: 1
Published Application/Species/Sample/DilutionReference
  • western blot; human
Day T, Palle K, Barkley L, Kakusho N, Zou Y, Tateishi S, et al. Phosphorylated Rad18 directs DNA polymerase η to sites of stalled replication. J Cell Biol. 2010;191:953-66 pubmed publisher
product information
catalog number :
MBS120101
products type :
Antibody
products full name :
Mouse monoclonal antibody Anti-Human DBF4
products short name :
DBF4
products name syn :
Homo sapiens DBF4 homolog (S. cerevisiae) (DBF4), mRNA; ASK; DBF4A
other names :
Homo sapiens DBF4 zinc finger (DBF4), mRNA; Protein DBF4 homolog A; protein DBF4 homolog A; DBF4 zinc finger A; DBF4-type zinc finger-containing protein 1; activator of S phase kinase; chiffon homolog A; zinc finger, DBF-type containing 1; DBF4 zinc finger; Activator of S phase kinase; Chiffon homolog A; DBF4-type zinc finger-containing protein 1
products gene name :
DBF4
other gene names :
DBF4; DBF4; ASK; CHIF; DBF4A; ZDBF1
uniprot entry name :
DBF4A_HUMAN
clonality :
Monoclonal
isotype :
IgG1
clone :
2047C4a
host :
Mouse
reactivity :
Human
sequence length :
3923
concentration :
100 ug/ml (1.0 ml)
tested application :
Dot Blot (DB)
other info1 :
Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum.
other info2 :
Sterility: Filtered through a 0.22 um membrane.
products description :
Play a role as a regulatory subunit for CDC7 which activates its kinase activity. Is required for entry into S phase. The complex CDC7-DBF4 selectively phosphorylates MCM2 subunit of chromatin-associated MCM complex and then is involved in regulating the initiation of DNA replication during cell cycle{EC1,EC2}. [UniProtKB Function]
ncbi gi num :
41393589
ncbi acc num :
NP_006707.1
ncbi gb acc num :
NM_006716
ncbi mol weight :
26,124 Da
ncbi pathways :
Activation Of ATR In Response To Replication Stress Pathway (105754); Activation Of The Pre-replicative Complex Pathway (105777); Cell Cycle Pathway (530733); Cell Cycle Checkpoints Pathway (105739); Cell Cycle, Mitotic Pathway (105765); Cell Cycle Pathway (198811); Cell Cycle Pathway (83054); Cell Cycle Pathway (463); DNA Replication Pathway (198771); DNA Replication Pathway (105897)
uniprot summary :
DBF4: DBF4. Protein type: Protein kinase, regulatory subunit; Cell cycle regulation. Chromosomal Location of Human Ortholog: 7q21.3. Cellular Component: nucleoplasm. Molecular Function: nucleic acid binding; zinc ion binding; enzyme activator activity. Biological Process: positive regulation of catalytic activity; mitotic cell cycle; DNA replication; G1/S transition of mitotic cell cycle
size1 :
0.1 mg
price1 :
345 USD
company information
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com
1-888-627-0165
headquarters: USA
MyBioSource, LLC was orginally founded in Vancouver by three enthusiastic scientists who are passionate about providing the world with the best reagents available. Together, they form a company with a big vision known as MyBioSource. MyBioSource is now located in San Diego, California, USA.

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